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A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours.
Cui C, Chakraborty K, Tang XA, Schoenfelt KQ, Hoffman A, Blank A, McBeth B, Pulliam N, Reardon CA, Kulkarni SA, Vaisar T, Ballabio A, Krishnan Y, Becker L. Cui C, et al. Among authors: chakraborty k. Nat Nanotechnol. 2021 Dec;16(12):1394-1402. doi: 10.1038/s41565-021-00988-z. Epub 2021 Nov 11. Nat Nanotechnol. 2021. PMID: 34764452
A DNA nanomachine chemically resolves lysosomes in live cells.
Leung K, Chakraborty K, Saminathan A, Krishnan Y. Leung K, et al. Among authors: chakraborty k. Nat Nanotechnol. 2019 Feb;14(2):176-183. doi: 10.1038/s41565-018-0318-5. Epub 2018 Dec 3. Nat Nanotechnol. 2019. PMID: 30510277 Free PMC article.
DNA nanodevices map enzymatic activity in organelles.
Dan K, Veetil AT, Chakraborty K, Krishnan Y. Dan K, et al. Among authors: chakraborty k. Nat Nanotechnol. 2019 Mar;14(3):252-259. doi: 10.1038/s41565-019-0365-6. Epub 2019 Feb 11. Nat Nanotechnol. 2019. PMID: 30742135 Free PMC article.
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Cui C, Chakraborty K, Tang XA, Zhou G, Schoenfelt KQ, Becker KM, Hoffman A, Chang YF, Blank A, Reardon CA, Kenny HA, Vaisar T, Lengyel E, Greene G, Becker L. Cui C, et al. Among authors: chakraborty k. Cell. 2021 Jun 10;184(12):3163-3177.e21. doi: 10.1016/j.cell.2021.04.016. Epub 2021 May 7. Cell. 2021. PMID: 33964209 Free PMC article.
A pH-correctable, DNA-based fluorescent reporter for organellar calcium.
Narayanaswamy N, Chakraborty K, Saminathan A, Zeichner E, Leung K, Devany J, Krishnan Y. Narayanaswamy N, et al. Among authors: chakraborty k. Nat Methods. 2019 Jan;16(1):95-102. doi: 10.1038/s41592-018-0232-7. Epub 2018 Dec 10. Nat Methods. 2019. PMID: 30532082 Free PMC article.
475 results