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A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours.
Cui C, Chakraborty K, Tang XA, Schoenfelt KQ, Hoffman A, Blank A, McBeth B, Pulliam N, Reardon CA, Kulkarni SA, Vaisar T, Ballabio A, Krishnan Y, Becker L. Cui C, et al. Among authors: schoenfelt kq. Nat Nanotechnol. 2021 Dec;16(12):1394-1402. doi: 10.1038/s41565-021-00988-z. Epub 2021 Nov 11. Nat Nanotechnol. 2021. PMID: 34764452
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Cui C, Chakraborty K, Tang XA, Zhou G, Schoenfelt KQ, Becker KM, Hoffman A, Chang YF, Blank A, Reardon CA, Kenny HA, Vaisar T, Lengyel E, Greene G, Becker L. Cui C, et al. Among authors: schoenfelt kq. Cell. 2021 Jun 10;184(12):3163-3177.e21. doi: 10.1016/j.cell.2021.04.016. Epub 2021 May 7. Cell. 2021. PMID: 33964209 Free PMC article.
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity.
Coats BR, Schoenfelt KQ, Barbosa-Lorenzi VC, Peris E, Cui C, Hoffman A, Zhou G, Fernandez S, Zhai L, Hall BA, Haka AS, Shah AM, Reardon CA, Brady MJ, Rhodes CJ, Maxfield FR, Becker L. Coats BR, et al. Among authors: schoenfelt kq. Cell Rep. 2017 Sep 26;20(13):3149-3161. doi: 10.1016/j.celrep.2017.08.096. Cell Rep. 2017. PMID: 28954231 Free PMC article.
Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages.
Kratz M, Coats BR, Hisert KB, Hagman D, Mutskov V, Peris E, Schoenfelt KQ, Kuzma JN, Larson I, Billing PS, Landerholm RW, Crouthamel M, Gozal D, Hwang S, Singh PK, Becker L. Kratz M, et al. Among authors: schoenfelt kq. Cell Metab. 2014 Oct 7;20(4):614-25. doi: 10.1016/j.cmet.2014.08.010. Epub 2014 Sep 18. Cell Metab. 2014. PMID: 25242226 Free PMC article.
18 results