Abdel-Rahman HM - Search Results

1

Synthesis, biological evaluation, and molecular modeling studies of acetophenones-tethered 1,2,4-triazoles and their oximes as epidermal growth factor receptor inhibitors.

El-Wahab HAAA, Ali AM, Abdel-Rahman HM, Qayed WS. El-Wahab HAAA, et al. Chem Biol Drug Des. 2022 Dec;100(6):981-993. doi: 10.1111/cbdd.13982. Epub 2021 Nov 22. Chem Biol Drug Des. 2022. PMID: 34773452

2

Design, synthesis and evaluation against Mycobacterium tuberculosis of azole piperazine derivatives as dicyclotyrosine (cYY) mimics.

El-Wahab HAAA, Accietto M, Marino LB, McLean KJ, Levy CW, Abdel-Rahman HM, El-Gendy MA, Munro AW, Aboraia AS, Simons C. El-Wahab HAAA, et al. Bioorg Med Chem. 2018 Jan 1;26(1):161-176. doi: 10.1016/j.bmc.2017.11.030. Epub 2017 Nov 21. Bioorg Med Chem. 2018. PMID: 29183661 Free article.

3

Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors.

El-Sherief HAM, Youssif BGM, Abbas Bukhari SN, Abdelazeem AH, Abdel-Aziz M, Abdel-Rahman HM. El-Sherief HAM, et al. Eur J Med Chem. 2018 Aug 5;156:774-789. doi: 10.1016/j.ejmech.2018.07.024. Epub 2018 Jul 10. Eur J Med Chem. 2018. PMID: 30055463

4

Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers.

Amin NH, Elsaadi MT, Zaki SS, Abdel-Rahman HM. Amin NH, et al. Bioorg Chem. 2020 Dec;105:104358. doi: 10.1016/j.bioorg.2020.104358. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33074119

5

Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies.

Abdel-Rahman HM, Abdel-Aziz M, Canzoneri JC, Gary BD, Piazza GA. Abdel-Rahman HM, et al. Arch Pharm (Weinheim). 2014 Sep;347(9):650-7. doi: 10.1002/ardp.201400083. Epub 2014 Jul 1. Arch Pharm (Weinheim). 2014. PMID: 24985336

6

Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors.

Abdel-Rahman HM, Abdel-Aziz M, Tinsley HN, Gary BD, Canzoneri JC, Piazza GA. Abdel-Rahman HM, et al. Arch Pharm (Weinheim). 2016 Feb;349(2):104-11. doi: 10.1002/ardp.201500363. Epub 2015 Dec 20. Arch Pharm (Weinheim). 2016. PMID: 26686665

7

Design, Synthesis, Antimicrobial Evaluation and Molecular Modeling Study of 1,2,4-Triazole-Based 4-Thiazolidinones.

Ahmed S, Zayed MF, El-Messery SM, Al-Agamy MH, Abdel-Rahman HM. Ahmed S, et al. Molecules. 2016 Apr 30;21(5):568. doi: 10.3390/molecules21050568. Molecules. 2016. PMID: 27144547 Free PMC article.

8

Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies.

El-Sherief HAM, Youssif BGM, Bukhari SNA, Abdel-Aziz M, Abdel-Rahman HM. El-Sherief HAM, et al. Bioorg Chem. 2018 Feb;76:314-325. doi: 10.1016/j.bioorg.2017.12.013. Epub 2017 Dec 5. Bioorg Chem. 2018. PMID: 29227915

9

Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities.

El-Sherief HAM, Youssif BGM, Abdelazeem AH, Abdel-Aziz M, Abdel-Rahman HM. El-Sherief HAM, et al. Anticancer Agents Med Chem. 2019;19(5):697-706. doi: 10.2174/1871520619666181224115346. Anticancer Agents Med Chem. 2019. PMID: 30582484

10

Design and synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity.

Abd El-Aleam RH, George RF, Lee KJ, Keeton AB, Piazza GA, Kamel AA, El-Daly ME, Hassan GS, Abdel-Rahman HM. Abd El-Aleam RH, et al. Arch Pharm (Weinheim). 2019 Aug;352(8):e1900002. doi: 10.1002/ardp.201900002. Epub 2019 Jul 29. Arch Pharm (Weinheim). 2019. PMID: 31353608

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