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Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A.
Bourahla K, Guihéneuf S, Limanton E, Paquin L, Le Guével R, Charlier T, Rahmouni M, Durieu E, Lozach O, Carreaux F, Meijer L, Bazureau JP. Bourahla K, et al. Among authors: lozach o. Pharmaceuticals (Basel). 2021 Oct 27;14(11):1086. doi: 10.3390/ph14111086. Pharmaceuticals (Basel). 2021. PMID: 34832868 Free PMC article.
Synthesis and kinase inhibitory activity of novel substituted indigoids.
Beauchard A, Laborie H, Rouillard H, Lozach O, Ferandin Y, Le Guével R, Guguen-Guillouzo C, Meijer L, Besson T, Thiéry V. Beauchard A, et al. Among authors: lozach o. Bioorg Med Chem. 2009 Sep 1;17(17):6257-63. doi: 10.1016/j.bmc.2009.07.051. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19665384
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Debdab M, Carreaux F, Renault S, Soundararajan M, Fedorov O, Filippakopoulos P, Lozach O, Babault L, Tahtouh T, Baratte B, Ogawa Y, Hagiwara M, Eisenreich A, Rauch U, Knapp S, Meijer L, Bazureau JP. Debdab M, et al. Among authors: lozach o. J Med Chem. 2011 Jun 23;54(12):4172-86. doi: 10.1021/jm200274d. Epub 2011 May 26. J Med Chem. 2011. PMID: 21615147
Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.
Boulahjar R, Ouach A, Bourg S, Bonnet P, Lozach O, Meijer L, Guguen-Guillouzo C, Le Guevel R, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: lozach o. Eur J Med Chem. 2015 Aug 28;101:274-87. doi: 10.1016/j.ejmech.2015.06.046. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26142492 Free article.
73 results