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Page 1
Parkinson's Disease-Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.
Streubel-Gallasch L, Giusti V, Sandre M, Tessari I, Plotegher N, Giusto E, Masato A, Iovino L, Battisti I, Arrigoni G, Shimshek D, Greggio E, Tremblay ME, Bubacco L, Erlandsson A, Civiero L. Streubel-Gallasch L, et al. Mol Neurobiol. 2021 Jul;58(7):3119-3140. doi: 10.1007/s12035-021-02327-8. Epub 2021 Feb 24. Mol Neurobiol. 2021. PMID: 33629273 Free PMC article.
CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN 1 M146L mutation.
Konstantinidis E, Molisak A, Perrin F, Streubel-Gallasch L, Fayad S, Kim DY, Petri K, Aryee MJ, Aguilar X, György B, Giedraitis V, Joung JK, Pattanayak V, Essand M, Erlandsson A, Berezovska O, Ingelsson M. Konstantinidis E, et al. Among authors: streubel gallasch l. Mol Ther Nucleic Acids. 2022 Mar 28;28:450-461. doi: 10.1016/j.omtn.2022.03.022. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35505961 Free PMC article.
Astrocytic uptake of neuronal corpses promotes cell-to-cell spreading of tau pathology.
Mothes T, Portal B, Konstantinidis E, Eltom K, Libard S, Streubel-Gallasch L, Ingelsson M, Rostami J, Lindskog M, Erlandsson A. Mothes T, et al. Among authors: streubel gallasch l. Acta Neuropathol Commun. 2023 Jun 17;11(1):97. doi: 10.1186/s40478-023-01589-8. Acta Neuropathol Commun. 2023. PMID: 37330529 Free PMC article.
α-Synuclein Pathology in PRKN-Linked Parkinson's Disease: New Insights from a Blood-Based Seed Amplification Assay.
Kluge A, Borsche M, Streubel-Gallasch L, Gül T, Schaake S, Balck A, Prasuhn J, Campbell P, Morris HR, Schapira AH, Lohmann K, Brüggemann N, Rakovic A, Seibler P, Başak AN, Berg D, Klein C. Kluge A, et al. Among authors: streubel gallasch l. Ann Neurol. 2024 Jun;95(6):1173-1177. doi: 10.1002/ana.26917. Epub 2024 Mar 28. Ann Neurol. 2024. PMID: 38546204
Characterization of the pathogenic α-Synuclein Variant V15A in Parkinson´s disease.
Diaw SH, Borsche M, Streubel-Gallasch L, Dulovic-Mahlow M, Hermes J, Lenz I, Seibler P, Klein C, Brüggemann N, Vos M, Lohmann K. Diaw SH, et al. Among authors: streubel gallasch l. NPJ Parkinsons Dis. 2023 Oct 30;9(1):148. doi: 10.1038/s41531-023-00584-z. NPJ Parkinsons Dis. 2023. PMID: 37903765 Free PMC article.