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Page 1
Retinol Saturase: More than the Name Suggests.
Weber P, Flores RE, Kiefer MF, Schupp M. Weber P, et al. Among authors: flores re. Trends Pharmacol Sci. 2020 Jun;41(6):418-427. doi: 10.1016/j.tips.2020.03.007. Epub 2020 Apr 25. Trends Pharmacol Sci. 2020. PMID: 32345479 Review.
Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis.
Oster M, Galhuber M, Krstic J, Steinhoff JS, Lenihan-Geels G, Wulff S, Kiefer MF, Petricek KM, Wowro SJ, Flores RE, Yang N, Li C, Meng Y, Reinisch I, Sommerfeld M, Weger S, Habisch H, Madl T, Schulz TJ, Prokesch A, Schupp M. Oster M, et al. Among authors: flores re. J Biol Chem. 2022 Sep;298(9):102287. doi: 10.1016/j.jbc.2022.102287. Epub 2022 Jul 20. J Biol Chem. 2022. PMID: 35868560 Free PMC article.
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression.
Steinhoff JS, Wagner C, Taschler U, Wulff S, Kiefer MF, Petricek KM, Wowro SJ, Oster M, Flores RE, Yang N, Li C, Meng Y, Sommerfeld M, Weger S, Henze A, Raila J, Lass A, Schupp M. Steinhoff JS, et al. Among authors: flores re. J Lipid Res. 2022 Oct;63(10):100268. doi: 10.1016/j.jlr.2022.100268. Epub 2022 Aug 27. J Lipid Res. 2022. PMID: 36030930 Free PMC article.
Adipose retinol saturase is regulated by β-adrenergic signaling and its deletion impairs lipolysis in adipocytes and acute cold tolerance in mice.
Li C, Kiefer MF, Dittrich S, Flores RE, Meng Y, Yang N, Wulff S, Gohlke S, Sommerfeld M, Wowro SJ, Petricek KM, Dürbeck D, Spranger L, Mai K, Scholz H, Schulz TJ, Schupp M. Li C, et al. Among authors: flores re. Mol Metab. 2024 Jan;79:101855. doi: 10.1016/j.molmet.2023.101855. Epub 2023 Dec 19. Mol Metab. 2024. PMID: 38128827 Free PMC article.
Adipocyte HSL is required for maintaining circulating vitamin A and RBP4 levels during fasting.
Steinhoff JS, Wagner C, Dähnhardt HE, Košić K, Meng Y, Taschler U, Pajed L, Yang N, Wulff S, Kiefer MF, Petricek KM, Flores RE, Li C, Dittrich S, Sommerfeld M, Guillou H, Henze A, Raila J, Wowro SJ, Schoiswohl G, Lass A, Schupp M. Steinhoff JS, et al. Among authors: flores re. EMBO Rep. 2024 Jul;25(7):2878-2895. doi: 10.1038/s44319-024-00158-x. Epub 2024 May 20. EMBO Rep. 2024. PMID: 38769419 Free PMC article.
Intestinal retinol saturase is implicated in the development of obesity and epithelial homeostasis upon injury.
Kiefer MF, Meng Y, Yang N, Vahrenbrink M, Wulff S, Li C, Wowro SJ, Petricek KM, Sommerfeld M, Flores RE, Obermayer B, Piepelow K, Klaus S, Hartl K, Guillot A, Tacke F, Sigal M, Schupp M. Kiefer MF, et al. Among authors: flores re. Am J Physiol Endocrinol Metab. 2024 Aug 1;327(2):E203-E216. doi: 10.1152/ajpendo.00035.2024. Epub 2024 Jun 19. Am J Physiol Endocrinol Metab. 2024. PMID: 38895981
p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl K, Bayram Ş, Wetzel A, Harnack C, Lin M, Fischer AS, Liu L, Beccaceci G, Mastrobuoni G, Geisberger S, Forbes M, Monteiro BJE, Macino M, Flores RE, Engelmann C, Mollenkopf HJ, Schupp M, Tacke F, Sanders AD, Kempa S, Berger H, Sigal M. Hartl K, et al. Among authors: flores re. Sci Adv. 2024 Oct 25;10(43):eadp8783. doi: 10.1126/sciadv.adp8783. Epub 2024 Oct 25. Sci Adv. 2024. PMID: 39453996 Free PMC article.
Safety of the PCSK9 inhibitor alirocumab: insights from 47 296 patient-years of observation.
Goodman SG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Harrington RA, Jukema JW, White HD, Zeiher AM, Manvelian G, Pordy R, Poulouin Y, Stipek W, Garon G, Schwartz GG; ODYSSEY OUTCOMES Investigators. Goodman SG, et al. Eur Heart J Cardiovasc Pharmacother. 2024 Jul 16;10(4):342-352. doi: 10.1093/ehjcvp/pvae025. Eur Heart J Cardiovasc Pharmacother. 2024. PMID: 38658193 Free PMC article. Review.
23 results