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A new mouse model of Ehlers-Danlos syndrome generated using CRISPR/Cas9-mediated genomic editing.
Nitahara-Kasahara Y, Mizumoto S, Inoue YU, Saka S, Posadas-Herrera G, Nakamura-Takahashi A, Takahashi Y, Hashimoto A, Konishi K, Miyata S, Masuda C, Matsumoto E, Maruoka Y, Yoshizawa T, Tanase T, Inoue T, Yamada S, Nomura Y, Takeda S, Watanabe A, Kosho T, Okada T. Nitahara-Kasahara Y, et al. Among authors: takahashi y. Dis Model Mech. 2021 Dec 1;14(12):dmm048963. doi: 10.1242/dmm.048963. Epub 2021 Dec 23. Dis Model Mech. 2021. PMID: 34850861 Free PMC article.
Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency.
Yoshizawa T, Mizumoto S, Takahashi Y, Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura Y, Nitahara-Kasahara Y, Okada T, Matsumoto K, Yamada S, Kosho T. Yoshizawa T, et al. Among authors: takahashi y. Glycobiology. 2018 Feb 1;28(2):80-89. doi: 10.1093/glycob/cwx099. Glycobiology. 2018. PMID: 29206923 Free PMC article.
Systematic investigation of the skin in Chst14-/- mice: A model for skin fragility in musculocontractural Ehlers-Danlos syndrome caused by CHST14 variants (mcEDS-CHST14).
Hirose T, Mizumoto S, Hashimoto A, Takahashi Y, Yoshizawa T, Nitahara-Kasahara Y, Takahashi N, Nakayama J, Takehana K, Okada T, Nomura Y, Yamada S, Kosho T, Watanabe T. Hirose T, et al. Among authors: takahashi n, takahashi y. Glycobiology. 2021 Feb 9;31(2):137-150. doi: 10.1093/glycob/cwaa058. Glycobiology. 2021. PMID: 32601684
New inducible mast cell-deficient mouse model (Mcpt5/Cma1DTR).
Sasaki H, Imanishi M, Fujikura D, Sugiyama M, Tanimoto K, Mochiji Y, Takahashi Y, Hiura K, Watanabe M, Kashimoto T, Nakano K, Okamura T, Sasaki N. Sasaki H, et al. Among authors: takahashi y. Biochem Biophys Res Commun. 2021 Apr 30;551:127-132. doi: 10.1016/j.bbrc.2021.03.025. Epub 2021 Mar 13. Biochem Biophys Res Commun. 2021. PMID: 33725574
Novel murine model of congenital diabetes: The insulin hyposecretion mouse.
Nakano K, Yanobu-Takanashi R, Takahashi Y, Sasaki H, Shimizu Y, Okamura T, Sasaki N. Nakano K, et al. Among authors: takahashi y. J Diabetes Investig. 2019 Mar;10(2):227-237. doi: 10.1111/jdi.12895. Epub 2018 Aug 17. J Diabetes Investig. 2019. PMID: 29987871 Free PMC article.
12,478 results
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