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Dual inhibition of TGF-β and PD-L1: a novel approach to cancer treatment.
Gulley JL, Schlom J, Barcellos-Hoff MH, Wang XJ, Seoane J, Audhuy F, Lan Y, Dussault I, Moustakas A. Gulley JL, et al. Mol Oncol. 2022 Jun;16(11):2117-2134. doi: 10.1002/1878-0261.13146. Epub 2022 Jan 4. Mol Oncol. 2022. PMID: 34854206 Free PMC article. Review.
Subjugation of TGFβ Signaling by Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma Shifts DNA Repair from Homologous Recombination to Alternative End Joining.
Liu Q, Ma L, Jones T, Palomero L, Pujana MA, Martinez-Ruiz H, Ha PK, Murnane J, Cuartas I, Seoane J, Baumann M, Linge A, Barcellos-Hoff MH. Liu Q, et al. Clin Cancer Res. 2018 Dec 1;24(23):6001-6014. doi: 10.1158/1078-0432.CCR-18-1346. Epub 2018 Aug 7. Clin Cancer Res. 2018. PMID: 30087144
Positron Emission Tomography Imaging of Functional Transforming Growth Factor β (TGFβ) Activity and Benefit of TGFβ Inhibition in Irradiated Intracranial Tumors.
Gonzalez-Junca A, Reiners O, Borrero-Garcia LD, Beckford-Vera D, Lazar AA, Chou W, Braunstein S, VanBrocklin H, Franc BL, Barcellos-Hoff MH. Gonzalez-Junca A, et al. Int J Radiat Oncol Biol Phys. 2021 Feb 1;109(2):527-539. doi: 10.1016/j.ijrobp.2020.09.043. Epub 2020 Sep 29. Int J Radiat Oncol Biol Phys. 2021. PMID: 33007434 Free PMC article.
Exploiting Canonical TGFβ Signaling in Cancer Treatment.
Liu Q, Chen G, Moore J, Guix I, Placantonakis D, Barcellos-Hoff MH. Liu Q, et al. Mol Cancer Ther. 2022 Jan;21(1):16-24. doi: 10.1158/1535-7163.MCT-20-0891. Epub 2021 Oct 20. Mol Cancer Ther. 2022. PMID: 34670783 Free PMC article. Review.
169 results