Zhang X - Search Results

1

Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity.

Ma C, Xia Z, Sacco MD, Hu Y, Townsend JA, Meng X, Choza J, Tan H, Jang J, Gongora MV, Zhang X, Zhang F, Xiang Y, Marty MT, Chen Y, Wang J. Ma C, et al. Among authors: zhang f, zhang x. J Am Chem Soc. 2021 Dec 15;143(49):20697-20709. doi: 10.1021/jacs.1c08060. Epub 2021 Dec 3. J Am Chem Soc. 2021. PMID: 34860011 Free PMC article.

2

Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity.

Smith EW, Zhang X, Behzadi C, Andrews LD, Cohen F, Chen Y. Smith EW, et al. Among authors: zhang x. Biochemistry. 2015 Sep 29;54(38):5937-48. doi: 10.1021/acs.biochem.5b00720. Epub 2015 Sep 18. Biochemistry. 2015. PMID: 26352800

3

Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2).

Pemberton OA, Zhang X, Chen Y. Pemberton OA, et al. Among authors: zhang x. J Med Chem. 2017 Apr 27;60(8):3525-3530. doi: 10.1021/acs.jmedchem.7b00158. Epub 2017 Apr 17. J Med Chem. 2017. PMID: 28388065 Free PMC article.

4

Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery.

Torelli NJ, Akhtar A, DeFrees K, Jaishankar P, Pemberton OA, Zhang X, Johnson C, Renslo AR, Chen Y. Torelli NJ, et al. Among authors: zhang x. ACS Infect Dis. 2019 Jun 14;5(6):1013-1021. doi: 10.1021/acsinfecdis.9b00052. Epub 2019 Apr 15. ACS Infect Dis. 2019. PMID: 30942078

5

Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography.

Kroeck KG, Sacco MD, Smith EW, Zhang X, Shoun D, Akhtar A, Darch SE, Cohen F, Andrews LD, Knox JE, Chen Y. Kroeck KG, et al. Among authors: zhang x. Sci Rep. 2019 Oct 29;9(1):15450. doi: 10.1038/s41598-019-51844-z. Sci Rep. 2019. PMID: 31664082 Free PMC article.

6

Influence of the α-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 β-Lactamase.

Sacco MD, Kroeck KG, Kemp MT, Zhang X, Andrews LD, Chen Y. Sacco MD, et al. Among authors: zhang x. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01473-19. doi: 10.1128/AAC.01473-19. Print 2019 Dec 20. Antimicrob Agents Chemother. 2019. PMID: 31685462 Free PMC article.

7

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.

Ma C, Sacco MD, Hurst B, Townsend JA, Hu Y, Szeto T, Zhang X, Tarbet B, Marty MT, Chen Y, Wang J. Ma C, et al. Among authors: zhang x. bioRxiv [Preprint]. 2020 Jan 6:2020.04.20.051581. doi: 10.1101/2020.04.20.051581. bioRxiv. 2020. Update in: Cell Res. 2020 Aug;30(8):678-692. doi: 10.1038/s41422-020-0356-z PMID: 32511378 Free PMC article. Updated. Preprint.

8

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.

Ma C, Sacco MD, Hurst B, Townsend JA, Hu Y, Szeto T, Zhang X, Tarbet B, Marty MT, Chen Y, Wang J. Ma C, et al. Among authors: zhang x. Cell Res. 2020 Aug;30(8):678-692. doi: 10.1038/s41422-020-0356-z. Epub 2020 Jun 15. Cell Res. 2020. PMID: 32541865 Free PMC article.

9

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M^pro and cathepsin L.

Sacco MD, Ma C, Lagarias P, Gao A, Townsend JA, Meng X, Dube P, Zhang X, Hu Y, Kitamura N, Hurst B, Tarbet B, Marty MT, Kolocouris A, Xiang Y, Chen Y, Wang J. Sacco MD, et al. Among authors: zhang x. bioRxiv [Preprint]. 2020 Jul 27:2020.07.27.223727. doi: 10.1101/2020.07.27.223727. bioRxiv. 2020. Update in: Sci Adv. 2020 Dec 9;6(50):eabe0751. doi: 10.1126/sciadv.abe0751 PMID: 32766590 Free PMC article. Updated. Preprint.

10

An Empirical Study of Amide-Heteroarene π-Stacking Interactions Using Reversible Inhibitors of a Bacterial Serine Hydrolase.

DeFrees K, Kemp MT, ElHilali-Pollard X, Zhang X, Mohamed A, Chen Y, Renslo AR. DeFrees K, et al. Among authors: zhang x. Org Chem Front. 2019 Jun 7;6(11):1749-1756. doi: 10.1039/c9qo00342h. Epub 2019 May 15. Org Chem Front. 2019. PMID: 32774871 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

180,911 results

Search Page

Filters