Jardetzky TS - Search Results

1

Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.

Pennington LF, Gasser P, Kleinboelting S, Zhang C, Skiniotis G, Eggel A, Jardetzky TS. Pennington LF, et al. Among authors: jardetzky ts. Nat Commun. 2021 Dec 3;12(1):7069. doi: 10.1038/s41467-021-27397-z. Nat Commun. 2021. PMID: 34862384 Free PMC article.

2

Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha.

Garman SC, Wurzburg BA, Tarchevskaya SS, Kinet JP, Jardetzky TS. Garman SC, et al. Among authors: jardetzky ts. Nature. 2000 Jul 20;406(6793):259-66. doi: 10.1038/35018500. Nature. 2000. PMID: 10917520

3

An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.

Wurzburg BA, Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. Wurzburg BA, et al. Among authors: jardetzky ts. J Biol Chem. 2012 Oct 19;287(43):36251-7. doi: 10.1074/jbc.M112.407502. Epub 2012 Sep 4. J Biol Chem. 2012. PMID: 22948141 Free PMC article.

4

A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions.

Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. Kim B, et al. Among authors: jardetzky ts. Anal Biochem. 2012 Dec 15;431(2):84-9. doi: 10.1016/j.ab.2012.09.010. Epub 2012 Sep 18. Anal Biochem. 2012. PMID: 22995065 Free PMC article.

5

Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.

Kim B, Eggel A, Tarchevskaya SS, Vogel M, Prinz H, Jardetzky TS. Kim B, et al. Among authors: jardetzky ts. Nature. 2012 Nov 22;491(7425):613-7. doi: 10.1038/nature11546. Epub 2012 Oct 28. Nature. 2012. PMID: 23103871 Free PMC article.

6

Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells.

Eggel A, Baravalle G, Hobi G, Kim B, Buschor P, Forrer P, Shin JS, Vogel M, Stadler BM, Dahinden CA, Jardetzky TS. Eggel A, et al. Among authors: jardetzky ts. J Allergy Clin Immunol. 2014 Jun;133(6):1709-19.e8. doi: 10.1016/j.jaci.2014.02.005. Epub 2014 Mar 15. J Allergy Clin Immunol. 2014. PMID: 24642143 Free PMC article.

7

Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.

Pennington LF, Tarchevskaya S, Brigger D, Sathiyamoorthy K, Graham MT, Nadeau KC, Eggel A, Jardetzky TS. Pennington LF, et al. Among authors: jardetzky ts. Nat Commun. 2016 May 19;7:11610. doi: 10.1038/ncomms11610. Nat Commun. 2016. PMID: 27194387 Free PMC article.

8

Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins.

Sathiyamoorthy K, Hu YX, Möhl BS, Chen J, Longnecker R, Jardetzky TS. Sathiyamoorthy K, et al. Among authors: jardetzky ts. Nat Commun. 2016 Dec 8;7:13557. doi: 10.1038/ncomms13557. Nat Commun. 2016. PMID: 27929061 Free PMC article.

9

H-IPSE Is a Pathogen-Secreted Host Nucleus-Infiltrating Protein (Infiltrin) Expressed Exclusively by the Schistosoma haematobium Egg Stage.

Pennington LF, Alouffi A, Mbanefo EC, Ray D, Heery DM, Jardetzky TS, Hsieh MH, Falcone FH. Pennington LF, et al. Among authors: jardetzky ts. Infect Immun. 2017 Nov 17;85(12):e00301-17. doi: 10.1128/IAI.00301-17. Print 2017 Dec. Infect Immun. 2017. PMID: 28923894 Free PMC article.

10

Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation.

Wong JJW, Young TA, Zhang J, Liu S, Leser GP, Komives EA, Lamb RA, Zhou ZH, Salafsky J, Jardetzky TS. Wong JJW, et al. Among authors: jardetzky ts. Nat Commun. 2017 Oct 3;8(1):781. doi: 10.1038/s41467-017-00863-3. Nat Commun. 2017. PMID: 28974687 Free PMC article.

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