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Page 1
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands.
Gado F, Ferrisi R, Polini B, Mohamed KA, Ricardi C, Lucarini E, Carpi S, Domenichini F, Stevenson LA, Rapposelli S, Saccomanni G, Nieri P, Ortore G, Pertwee RG, Ghelardini C, Di Cesare Mannelli L, Chiellini G, Laprairie RB, Manera C. Gado F, et al. Among authors: ferrisi r. J Med Chem. 2022 Jul 28;65(14):9918-9938. doi: 10.1021/acs.jmedchem.2c00582. Epub 2022 Jul 18. J Med Chem. 2022. PMID: 35849804 Free PMC article.
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells.
Gado F, Ferrisi R, Di Somma S, Napolitano F, Mohamed KA, Stevenson LA, Rapposelli S, Saccomanni G, Portella G, Pertwee RG, Laprairie RB, Malfitano AM, Manera C. Gado F, et al. Among authors: ferrisi r. Molecules. 2022 May 7;27(9):3019. doi: 10.3390/molecules27093019. Molecules. 2022. PMID: 35566369 Free PMC article.
Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.
Granchi C, Bononi G, Ferrisi R, Gori E, Mantini G, Glasmacher S, Poli G, Palazzolo S, Caligiuri I, Rizzolio F, Canzonieri V, Perin T, Gertsch J, Sodi A, Giovannetti E, Macchia M, Minutolo F, Tuccinardi T, Chicca A. Granchi C, et al. Among authors: ferrisi r. Eur J Med Chem. 2021 Jan 1;209:112857. doi: 10.1016/j.ejmech.2020.112857. Epub 2020 Oct 7. Eur J Med Chem. 2021. PMID: 33045662
A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells.
Polini B, Zallocco L, Gado F, Ferrisi R, Ricardi C, Zuccarini M, Carnicelli V, Manera C, Ronci M, Lucacchini A, Zucchi R, Giusti L, Chiellini G. Polini B, et al. Among authors: ferrisi r. Cells. 2024 May 19;13(10):875. doi: 10.3390/cells13100875. Cells. 2024. PMID: 38786097 Free PMC article.
13 results