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Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.
Proschak A, Martinelli G, Frank D, Rotter MJ, Brunst S, Weizel L, Burgers LD, Fürst R, Proschak E, Sosič I, Gobec S, Wichelhaus TA. Proschak A, et al. Among authors: martinelli g. Eur J Med Chem. 2022 Jan 15;228:113975. doi: 10.1016/j.ejmech.2021.113975. Epub 2021 Nov 13. Eur J Med Chem. 2022. PMID: 34865870
RhII -Catalyzed De-symmetrization of Ethane-1,2-dithiol and Propane-1,3-dithiol Yields Metallo-β-lactamase Inhibitors.
Krasavin M, Zhukovsky D, Solovyev I, Barkhatova D, Dar'in D, Frank D, Martinelli G, Weizel L, Proschak A, Rotter M, Kramer JS, Brunst S, Wichelhaus TA, Proschak E. Krasavin M, et al. Among authors: martinelli g. ChemMedChem. 2021 Nov 19;16(22):3410-3417. doi: 10.1002/cmdc.202100344. Epub 2021 Aug 3. ChemMedChem. 2021. PMID: 34184833 Free PMC article.
Assessment of circulating tumor DNA in patients with locally advanced rectal cancer treated with neoadjuvant therapy.
Molinari C, Marisi G, Laliotis G, Spickard E, Rapposelli IG, Petracci E, George GV, Dutta P, Sharma S, Malhotra M, Prochowski Iamurri A, Feliciani G, Liu MC, Ulivi P, Canale M, Saragoni L, Gallo G, Frassineti GL, Muratore M, Romeo A, Jurdi A, Martinelli G, Passardi A. Molinari C, et al. Among authors: martinelli g. Sci Rep. 2024 Nov 28;14(1):29536. doi: 10.1038/s41598-024-80855-8. Sci Rep. 2024. PMID: 39604448 Free PMC article.
Significant Advancements and Evolutions in Chimeric Antigen Receptor Design.
Gaimari A, De Lucia A, Nicolini F, Mazzotti L, Maltoni R, Rughi G, Zurlo M, Marchesini M, Juan M, Parras D, Cerchione C, Martinelli G, Bravaccini S, Tettamanti S, Pasetto A, Pasini L, Magnoni C, Gazzola L, Borges de Souza P, Mazza M. Gaimari A, et al. Among authors: martinelli g. Int J Mol Sci. 2024 Nov 13;25(22):12201. doi: 10.3390/ijms252212201. Int J Mol Sci. 2024. PMID: 39596267 Free PMC article. Review.
HDAC6 as a Prognostic Factor and Druggable Target in HER2-Positive Breast Cancer.
Cortesi M, Bravaccini S, Ravaioli S, Petracci E, Angeli D, Tumedei MM, Balzi W, Pirini F, Zanoni M, Possanzini P, Rocca A, Palleschi M, Ulivi P, Martinelli G, Maltoni R. Cortesi M, et al. Among authors: martinelli g. Cancers (Basel). 2024 Nov 6;16(22):3752. doi: 10.3390/cancers16223752. Cancers (Basel). 2024. PMID: 39594707 Free PMC article.
Exploring the role of PARP1 inhibition in enhancing antibody-drug conjugate therapy for acute leukemias: insights from DNA damage response pathway interactions.
Ghelli Luserna di Rorà A, Jandoubi M, Padella A, Ferrari A, Marranci A, Mazzotti C, Olimpico F, Ghetti M, Ledda L, Bochicchio MT, Paganelli M, Zanoni M, Cafaro A, Servili C, Galimberti S, Gottardi M, Rondoni M, Endri M, Onofrillo D, Audisio E, Marconi G, Simonetti G, Martinelli G. Ghelli Luserna di Rorà A, et al. Among authors: martinelli g. J Transl Med. 2024 Nov 26;22(1):1062. doi: 10.1186/s12967-024-05838-9. J Transl Med. 2024. PMID: 39587643 Free PMC article.
The molecular features of lung cancer stem cells (LCSCs) in dedifferentiation process-driven epigenetic alterations.
Masciale V, Banchelli F, Grisendi G, Samarelli AV, Raineri G, Rossi T, Zanoni M, Cortesi M, Bandini S, Ulivi P, Martinelli G, Stella F, Dominici M, Aramini B. Masciale V, et al. Among authors: martinelli g. J Biol Chem. 2024 Nov 13:107994. doi: 10.1016/j.jbc.2024.107994. Online ahead of print. J Biol Chem. 2024. PMID: 39547513 Free article. Review.
Long-term survival can be achieved in a significant fraction of older patients with core binding factor acute myeloid leukemia treated with intensive chemotherapy.
Mosna F, Borlenghi E, Litzow M, Byrd JC, Papayannidis C, Tecchio C, Ferrara F, Marcucci G, Cairoli R, Morgan EA, Gurrieri C, Yeung CCS, Deeg HJ, Capelli D, Candoni A, Gotlib JR, Lunghi M, Pullarkat S, Lanza F, Galimberti S, Forghieri F, Venditti A, Festuccia M, Audisio E, Marvalle D, Rigolin GM, Roti G, DiBona E, Visani G, Albano F, Eisfeld AK, Valent P, Huls G, Borthakur G, Krampera M, Martinelli G, Kröger N, Sperotto A, Gottardi M. Mosna F, et al. Among authors: martinelli g. Haematologica. 2024 Oct 10. doi: 10.3324/haematol.2024.285448. Online ahead of print. Haematologica. 2024. PMID: 39385741 Free article.
Deep Molecular Response Rate in Chronic Phase Chronic Myeloid Leukemia: Eligibility to Discontinuation Related to Time to Response and Different Frontline TKI in the Experience of the Gimema Labnet CML National Network.
Breccia M, Cucci R, Marsili G, Castagnetti F, Galimberti S, Izzo B, Sorà F, Soverini S, Messina M, Piciocchi A, Bonifacio M, Cilloni D, Iurlo A, Martinelli G, Rosti G, Stagno F, Fazi P, Vignetti M, Pane F. Breccia M, et al. Among authors: martinelli g. Clin Lymphoma Myeloma Leuk. 2024 Sep 7:S2152-2650(24)01802-0. doi: 10.1016/j.clml.2024.08.009. Online ahead of print. Clin Lymphoma Myeloma Leuk. 2024. PMID: 39322541
1,467 results