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Allogeneic ABCB5+ mesenchymal stem cells for treatment-refractory chronic venous ulcers: a phase I/IIa clinical trial.
Kerstan A, Dieter K, Niebergall-Roth E, Dachtler AK, Kraft K, Stücker M, Daeschlein G, Jünger M, Görge T, Meyer-Pannwitt U, Erfurt-Berge C, von Engelhardt C, Klare A, Pfeiffer C, Esterlechner J, Schröder HM, Gasser M, Waaga-Gasser AM, Goebeler M, Ballikaya S, Sadeghi S, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Kerstan A, et al. JID Innov. 2022 Jan;2(1):100067. doi: 10.1016/j.xjidi.2021.100067. Epub 2021 Oct 25. JID Innov. 2022. PMID: 34870260 Free PMC article.
ABCB5 Identifies Immunoregulatory Dermal Cells.
Schatton T, Yang J, Kleffel S, Uehara M, Barthel SR, Schlapbach C, Zhan Q, Dudeney S, Mueller H, Lee N, de Vries JC, Meier B, Vander Beken S, Kluth MA, Ganss C, Sharpe AH, Waaga-Gasser AM, Sayegh MH, Abdi R, Scharffetter-Kochanek K, Murphy GF, Kupper TS, Frank NY, Frank MH. Schatton T, et al. Cell Rep. 2015 Sep 8;12(10):1564-74. doi: 10.1016/j.celrep.2015.08.010. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321644 Free PMC article.
Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells.
Jiang D, Muschhammer J, Qi Y, Kügler A, de Vries JC, Saffarzadeh M, Sindrilaru A, Beken SV, Wlaschek M, Kluth MA, Ganss C, Frank NY, Frank MH, Preissner KT, Scharffetter-Kochanek K. Jiang D, et al. Stem Cells. 2016 Sep;34(9):2393-406. doi: 10.1002/stem.2417. Epub 2016 Jun 27. Stem Cells. 2016. PMID: 27299700 Free PMC article.
In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials.
Tappenbeck N, Schröder HM, Niebergall-Roth E, Hassinger F, Dehio U, Dieter K, Kraft K, Kerstan A, Esterlechner J, Frank NY, Scharffetter-Kochanek K, Murphy GF, Orgill DP, Beck J, Frank MH, Ganss C, Kluth MA. Tappenbeck N, et al. Cytotherapy. 2019 May;21(5):546-560. doi: 10.1016/j.jcyt.2018.12.005. Epub 2019 Mar 14. Cytotherapy. 2019. PMID: 30878384 Free PMC article.
Newly Defined ATP-Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron-Overload Wounds via Secretion of Interleukin-1 Receptor Antagonist.
Vander Beken S, de Vries JC, Meier-Schiesser B, Meyer P, Jiang D, Sindrilaru A, Ferreira FF, Hainzl A, Schatz S, Muschhammer J, Scheurmann NJ, Kampilafkos P, Seitz AM, Dürselen L, Ignatius A, Kluth MA, Ganss C, Wlaschek M, Singh K, Maity P, Frank NY, Frank MH, Scharffetter-Kochanek K. Vander Beken S, et al. Stem Cells. 2019 Aug;37(8):1057-1074. doi: 10.1002/stem.3022. Epub 2019 May 13. Stem Cells. 2019. PMID: 31002437 Free PMC article.
Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data.
Kerstan A, Niebergall-Roth E, Esterlechner J, Schröder HM, Gasser M, Waaga-Gasser AM, Goebeler M, Rak K, Schrüfer P, Endres S, Hagenbusch P, Kraft K, Dieter K, Ballikaya S, Stemler N, Sadeghi S, Tappenbeck N, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Kerstan A, et al. Cytotherapy. 2021 Feb;23(2):165-175. doi: 10.1016/j.jcyt.2020.08.012. Epub 2020 Oct 1. Cytotherapy. 2021. PMID: 33011075 Free PMC article.
Angiogenin Released from ABCB5+ Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis.
Singh K, Maity P, Koroma AK, Basu A, Pandey RK, Vander Beken S, Haas P, Krug L, Hainzl A, Sindrilaru A, Pfeiffer C, Wlaschek M, Frank NY, Frank MH, Ganss C, Bánvölgyi A, Wikonkál N, Eming S, Pastar I, Tomic-Canic M, Kluth MA, Scharffetter-Kochanek K. Singh K, et al. J Invest Dermatol. 2022 Jun;142(6):1725-1736.e10. doi: 10.1016/j.jid.2021.10.026. Epub 2021 Nov 20. J Invest Dermatol. 2022. PMID: 34808236 Free PMC article.
Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers.
Kerstan A, Dieter K, Niebergall-Roth E, Klingele S, Jünger M, Hasslacher C, Daeschlein G, Stemler L, Meyer-Pannwitt U, Schubert K, Klausmann G, Raab T, Goebeler M, Kraft K, Esterlechner J, Schröder HM, Sadeghi S, Ballikaya S, Gasser M, Waaga-Gasser AM, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Kerstan A, et al. Stem Cell Res Ther. 2022 Sep 5;13(1):455. doi: 10.1186/s13287-022-03156-9. Stem Cell Res Ther. 2022. PMID: 36064604 Free PMC article. Clinical Trial.
Oxidative stress in chronic venous leg ulcers.
Wlaschek M, Scharffetter-Kochanek K. Wlaschek M, et al. Wound Repair Regen. 2005 Sep-Oct;13(5):452-61. doi: 10.1111/j.1067-1927.2005.00065.x. Wound Repair Regen. 2005. PMID: 16176453 Review.
[Necrotic papules on the abdomen].
Buback F, Pfeiffer C, Scharffetter-Kochanek K. Buback F, et al. Hautarzt. 2009 Aug;60(8):658-60, 662. doi: 10.1007/s00105-009-1773-6. Hautarzt. 2009. PMID: 19629413 German.
367 results