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Improving antibody drug development using bionanotechnology.
Makowski EK, Schardt JS, Tessier PM. Makowski EK, et al. Among authors: schardt js. Curr Opin Biotechnol. 2022 Apr;74:137-145. doi: 10.1016/j.copbio.2021.10.027. Epub 2021 Dec 7. Curr Opin Biotechnol. 2022. PMID: 34890875 Free PMC article. Review.
Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis.
Zupancic JM, Desai AA, Schardt JS, Pornnoppadol G, Makowski EK, Smith MD, Kennedy AA, Garcia de Mattos Barbosa M, Cascalho M, Lanigan TM, Tai AW, Tessier PM. Zupancic JM, et al. Among authors: schardt js. Cell Chem Biol. 2021 Sep 16;28(9):1379-1388.e7. doi: 10.1016/j.chembiol.2021.05.019. Epub 2021 Jun 24. Cell Chem Biol. 2021. PMID: 34171229 Free PMC article.
Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS-CoV-2 Variants.
Zupancic JM, Schardt JS, Desai AA, Makowski EK, Smith MD, Pornnoppadol G, Garcia de Mattos Barbosa M, Cascalho M, Lanigan TM, Tessier PM. Zupancic JM, et al. Among authors: schardt js. Adv Ther (Weinh). 2021 Aug;4(8):2100099. doi: 10.1002/adtp.202100099. Epub 2021 Aug 2. Adv Ther (Weinh). 2021. PMID: 34514086 Free PMC article.
Facile generation of biepitopic antibodies with intrinsic agonism for activating receptors in the tumor necrosis factor superfamily.
Jhajj HS, Schardt JS, Khalasawi N, Yao EL, Lwo TS, Kwon NY, O'Meara RL, Desai AA, Tessier PM. Jhajj HS, et al. Among authors: schardt js. bioRxiv [Preprint]. 2023 Dec 12:2023.12.11.571146. doi: 10.1101/2023.12.11.571146. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 May 16;31(5):944-954.e5. doi: 10.1016/j.chembiol.2024.03.010. PMID: 38168220 Free PMC article. Updated. Preprint.
19 results