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Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
Raveendra-Panickar D, Finlay D, Layng FI, Lambert LJ, Celeridad M, Zhao M, Barbosa K, De Backer LJS, Kwong E, Gosalia P, Rodiles S, Holleran J, Ardecky R, Grotegut S, Olson S, Hutchinson JH, Pasquale EB, Vuori K, Deshpande AJ, Cosford NDP, Tautz L. Raveendra-Panickar D, et al. Among authors: tautz l. J Biol Chem. 2022 Jan;298(1):101477. doi: 10.1016/j.jbc.2021.101477. Epub 2021 Dec 10. J Biol Chem. 2022. PMID: 34896393 Free PMC article.
Yersinia phosphatase induces mitochondrially dependent apoptosis of T cells.
Bruckner S, Rhamouni S, Tautz L, Denault JB, Alonso A, Becattini B, Salvesen GS, Mustelin T. Bruckner S, et al. Among authors: tautz l. J Biol Chem. 2005 Mar 18;280(11):10388-94. doi: 10.1074/jbc.M408829200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632192 Free article.
An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity.
Dawson MI, Xia Z, Liu G, Ye M, Fontana JA, Farhana L, Patel BB, Arumugarajah S, Bhuiyan M, Zhang XK, Han YH, Stallcup WB, Fukushi J, Mustelin T, Tautz L, Su Y, Harris DL, Waleh N, Hobbs PD, Jong L, Chao WR, Schiff LJ, Sani BP. Dawson MI, et al. Among authors: tautz l. J Med Chem. 2007 May 31;50(11):2622-39. doi: 10.1021/jm0613323. Epub 2007 May 10. J Med Chem. 2007. PMID: 17489579 Free PMC article.
Protein tyrosine phosphatases in autoimmunity.
Vang T, Miletic AV, Arimura Y, Tautz L, Rickert RC, Mustelin T. Vang T, et al. Among authors: tautz l. Annu Rev Immunol. 2008;26:29-55. doi: 10.1146/annurev.immunol.26.021607.090418. Annu Rev Immunol. 2008. PMID: 18303998 Review.
82 results