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Peripheral leukemia burden at time of apheresis negatively affects the clinical efficacy of CART19 in refractory or relapsed B-ALL.
Deng B, Pan J, Liu Z, Liu S, Chen Y, Qu X, Zhang Y, Lin Y, Zhang Y, Yu X, Zhang Z, Niu X, Luan R, Ma M, Li X, Liu T, Wu X, Niu H, Chang AH, Tong C. Deng B, et al. Among authors: chang ah. Mol Ther Methods Clin Dev. 2021 Oct 27;23:633-643. doi: 10.1016/j.omtm.2021.10.006. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34901308 Free PMC article.
CD22 CAR T-cell therapy in refractory or relapsed B acute lymphoblastic leukemia.
Pan J, Niu Q, Deng B, Liu S, Wu T, Gao Z, Liu Z, Zhang Y, Qu X, Zhang Y, Liu S, Ling Z, Lin Y, Zhao Y, Song Y, Tan X, Zhang Y, Li Z, Yin Z, Chen B, Yu X, Yan J, Zheng Q, Zhou X, Gao J, Chang AH, Feng X, Tong C. Pan J, et al. Among authors: chang ah. Leukemia. 2019 Dec;33(12):2854-2866. doi: 10.1038/s41375-019-0488-7. Epub 2019 May 20. Leukemia. 2019. PMID: 31110217 Clinical Trial.
Single-Cell Transcriptomic Analysis Reveals BCMA CAR-T Cell Dynamics in a Patient with Refractory Primary Plasma Cell Leukemia.
Li X, Guo X, Zhu Y, Wei G, Zhang Y, Li X, Xu H, Cui J, Wu W, He J, Ritchie ME, Weiskittel TM, Li H, Yu H, Ding L, Shao M, Luo Q, Xu X, Teng X, Chang AH, Zhang J, Huang H, Hu Y. Li X, et al. Among authors: chang ah. Mol Ther. 2021 Feb 3;29(2):645-657. doi: 10.1016/j.ymthe.2020.11.028. Epub 2020 Dec 3. Mol Ther. 2021. PMID: 33278564 Free PMC article.
Ruxolitinib mitigates steroid-refractory CRS during CAR T therapy.
Pan J, Deng B, Ling Z, Song W, Xu J, Duan J, Wang Z, Chang AH, Feng X, Tan Y. Pan J, et al. Among authors: chang ah. J Cell Mol Med. 2021 Jan;25(2):1089-1099. doi: 10.1111/jcmm.16176. Epub 2020 Dec 12. J Cell Mol Med. 2021. PMID: 33314568 Free PMC article. Clinical Trial.
312 results