Hirai H - Search Results

1

RUNX1 transactivates BCR-ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia.

Masuda T, Maeda S, Shimada S, Sakuramoto N, Morita K, Koyama A, Suzuki K, Mitsuda Y, Matsuo H, Kubota H, Kato I, Tanaka K, Takita J, Hirata M, Kataoka TR, Nakahata T, Adachi S, Hirai H, Mizuta S, Naka K, Imai Y, Kimura S, Sugiyama H, Kamikubo Y. Masuda T, et al. Among authors: hirai h. Cancer Sci. 2022 Feb;113(2):529-539. doi: 10.1111/cas.15239. Epub 2021 Dec 28. Cancer Sci. 2022. PMID: 34902205 Free PMC article.

2

Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells.

Takeuchi M, Ashihara E, Yamazaki Y, Kimura S, Nakagawa Y, Tanaka R, Yao H, Nagao R, Hayashi Y, Hirai H, Maekawa T. Takeuchi M, et al. Among authors: hirai h. Cancer Sci. 2011 Mar;102(3):591-6. doi: 10.1111/j.1349-7006.2010.01813.x. Epub 2010 Dec 19. Cancer Sci. 2011. PMID: 21166958 Free article.

3

Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients.

Tanaka R, Kimura S, Ashihara E, Yoshimura M, Takahashi N, Wakita H, Itoh K, Nishiwaki K, Suzuki K, Nagao R, Yao H, Hayashi Y, Satake S, Hirai H, Sawada K, Ottmann OG, Melo JV, Maekawa T. Tanaka R, et al. Among authors: hirai h. Cancer Lett. 2011 Dec 22;312(2):228-34. doi: 10.1016/j.canlet.2011.08.009. Epub 2011 Aug 22. Cancer Lett. 2011. PMID: 21890264

4

Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65--a novel Wnt/β-catenin signaling inhibitor.

Nagao R, Ashihara E, Kimura S, Strovel JW, Yao H, Takeuchi M, Tanaka R, Hayashi Y, Hirai H, Padia J, Strand K, Maekawa T. Nagao R, et al. Among authors: hirai h. Cancer Lett. 2011 Dec 15;312(1):91-100. doi: 10.1016/j.canlet.2011.08.002. Epub 2011 Aug 17. Cancer Lett. 2011. PMID: 21906872 Free article.

5

Targeting DNMT1 by demethylating agent OR-2100 increases tyrosine kinase inhibitors-sensitivity and depletes leukemic stem cells in chronic myeloid leukemia.

Kamachi K, Ureshino H, Watanabe T, Yoshida N, Yamamoto Y, Kurahashi Y, Fukuda-Kurahashi Y, Hayashi Y, Hirai H, Yamashita S, Ushijima T, Okada S, Kimura S. Kamachi K, et al. Among authors: hirai h. Cancer Lett. 2022 Feb 1;526:273-283. doi: 10.1016/j.canlet.2021.11.032. Epub 2021 Dec 4. Cancer Lett. 2022. PMID: 34875342 Free article.

6

The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.

Tanaka T, Kurokawa M, Ueki K, Tanaka K, Imai Y, Mitani K, Okazaki K, Sagata N, Yazaki Y, Shibata Y, Kadowaki T, Hirai H. Tanaka T, et al. Among authors: hirai h. Mol Cell Biol. 1996 Jul;16(7):3967-79. doi: 10.1128/MCB.16.7.3967. Mol Cell Biol. 1996. PMID: 8668214 Free PMC article.

7

The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.

Tanaka K, Tanaka T, Kurokawa M, Imai Y, Ogawa S, Mitani K, Yazaki Y, Hirai H. Tanaka K, et al. Among authors: hirai h. Blood. 1998 Mar 1;91(5):1688-99. Blood. 1998. PMID: 9473235 Free article.

8

C/EBPβ is a critical mediator of IFN-α-induced exhaustion of chronic myeloid leukemia stem cells.

Yokota A, Hirai H, Sato R, Adachi H, Sato F, Hayashi Y, Sato A, Kamio N, Miura Y, Nakano M, Tenen DG, Kimura S, Tashiro K, Maekawa T. Yokota A, et al. Among authors: hirai h. Blood Adv. 2019 Feb 12;3(3):476-488. doi: 10.1182/bloodadvances.2018020503. Blood Adv. 2019. PMID: 30755436 Free PMC article.

9

A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.

Kawata E, Ashihara E, Nakagawa Y, Kiuchi T, Ogura M, Yao H, Sakai K, Tanaka R, Nagao R, Yokota A, Takeuchi M, Kimura S, Hirai H, Maekawa T. Kawata E, et al. Among authors: hirai h. Cancer Lett. 2010 Aug 28;294(2):245-53. doi: 10.1016/j.canlet.2010.02.008. Epub 2010 Mar 4. Cancer Lett. 2010. PMID: 20206440 Free article.

10

Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor.

Hirai H, Yokota A, Tamura A, Sato A, Maekawa T. Hirai H, et al. Cancer Sci. 2015 Jul;106(7):797-802. doi: 10.1111/cas.12690. Epub 2015 Jun 1. Cancer Sci. 2015. PMID: 25940801 Free PMC article.

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