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Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis.
Zhang XJ, She ZG, Wang J, Sun D, Shen LJ, Xiang H, Cheng X, Ji YX, Huang YP, Li PL, Yang X, Cheng Y, Ma JP, Wang HP, Hu Y, Hu F, Tian S, Tian H, Zhang P, Zhao GN, Wang L, Hu ML, Yang Q, Zhu LH, Cai J, Yang J, Zhang X, Ma X, Xu Q, Touyz RM, Liu PP, Loomba R, Wang Y, Li H. Zhang XJ, et al. Among authors: hu f, hu y, hu ml. Sci Transl Med. 2021 Dec 15;13(624):eabg8117. doi: 10.1126/scitranslmed.abg8117. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910546
Hepatocyte SH3RF2 Deficiency Is a Key Aggravator for NAFLD.
Yang X, Sun D, Xiang H, Wang S, Huang Y, Li L, Cheng X, Liu H, Hu F, Cheng Y, Ma T, Hu M, Tian H, Tian S, Zhou Y, Zhang P, Zhang XJ, Ji YX, Hu Y, Li H, She ZG. Yang X, et al. Hepatology. 2021 Sep;74(3):1319-1338. doi: 10.1002/hep.31863. Epub 2021 Aug 30. Hepatology. 2021. PMID: 33894019
TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease.
Zhao GN, Tian ZW, Tian T, Zhu ZP, Zhao WJ, Tian H, Cheng X, Hu FJ, Hu ML, Tian S, Ding T, Chen S, Ji YX, Zhang P, Zhang XJ, She ZG, Yuan Y, Chen W, Bai L, Li H. Zhao GN, et al. Among authors: hu fj, hu ml. Cell Metab. 2021 Aug 3;33(8):1640-1654.e8. doi: 10.1016/j.cmet.2021.05.014. Epub 2021 Jun 8. Cell Metab. 2021. PMID: 34107313 Free article.
Global Burden of Disease Study 2019 suggests that metabolic risk factors are the leading drivers of the burden of ischemic heart disease.
Wang W, Hu M, Liu H, Zhang X, Li H, Zhou F, Liu YM, Lei F, Qin JJ, Zhao YC, Chen Z, Liu W, Song X, Huang X, Zhu L, Ji YX, Zhang P, Zhang XJ, She ZG, Yang J, Yang H, Cai J, Li H. Wang W, et al. Cell Metab. 2021 Oct 5;33(10):1943-1956.e2. doi: 10.1016/j.cmet.2021.08.005. Epub 2021 Sep 2. Cell Metab. 2021. PMID: 34478633 Free article.
Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species.
Zhang XJ, Liu X, Hu M, Zhao GJ, Sun D, Cheng X, Xiang H, Huang YP, Tian RF, Shen LJ, Ma JP, Wang HP, Tian S, Gan S, Xu H, Liao R, Zou T, Ji YX, Zhang P, Cai J, Wang ZV, Meng G, Xu Q, Wang Y, Ma XL, Liu PP, Huang Z, Zhu L, She ZG, Zhang X, Bai L, Yang H, Lu Z, Li H. Zhang XJ, et al. Cell Metab. 2021 Oct 5;33(10):2059-2075.e10. doi: 10.1016/j.cmet.2021.08.014. Epub 2021 Sep 17. Cell Metab. 2021. PMID: 34536344 Free article.
368 results