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Bioreactor-produced iPSCs-derived dopaminergic neuron-containing neural microtissues innervate and normalize rotational bias in a dose-dependent manner in a Parkinson rat model.
Prudon N, Cordero-Espinoza L, Abarkan M, Gurchenkov B, Morel C, Lepleux M, De Luca V, Lartigue M, Cabanas H, Pujol N, Milvoy L, Morand P, Moncaubeig F, Wurtz H, Poinçot L, De Marco M, Jonckeau A, Pletenka J, Luquet E, Sovera A, Hardoüin J, Neves IJ, Machado-Hitau A, Schmit K, Piouceau L, Guilbert S, Manache-Alberici L, Lanero Fidalgo M, Dabée G, Dufourd T, Schroeder J, Alessandri K, Bezard E, Faggiani E, Feyeux M. Prudon N, et al. Among authors: dufourd t. Neurotherapeutics. 2024 Sep;21(5):e00436. doi: 10.1016/j.neurot.2024.e00436. Epub 2024 Oct 1. Neurotherapeutics. 2024. PMID: 39353832 Free PMC article.
Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use.
Goutaudier R, Joly F, Mallet D, Bartolomucci M, Guicherd D, Carcenac C, Vossier F, Dufourd T, Boulet S, Deransart C, Chovelon B, Carnicella S. Goutaudier R, et al. Among authors: dufourd t. Mol Psychiatry. 2023 Jan;28(1):463-474. doi: 10.1038/s41380-022-01848-5. Epub 2022 Nov 14. Mol Psychiatry. 2023. PMID: 36376463 Free PMC article.