Gruenhagen J - Search Results

1

Fast and versatile analysis of liposome encapsulation efficiency by nanoParticle exclusion chromatography.

Bian J, Girotti J, Fan Y, Levy ES, Zang N, Sethuraman V, Kou P, Zhang K, Gruenhagen J, Lin J. Bian J, et al. Among authors: gruenhagen j. J Chromatogr A. 2022 Jan 11;1662:462688. doi: 10.1016/j.chroma.2021.462688. Epub 2021 Nov 17. J Chromatogr A. 2022. PMID: 34915190

2

A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates.

Li Y, Gu C, Gruenhagen J, Zhang K, Yehl P, Chetwyn NP, Medley CD. Li Y, et al. Among authors: gruenhagen j. J Chromatogr A. 2015 May 8;1393:81-8. doi: 10.1016/j.chroma.2015.03.027. Epub 2015 Mar 16. J Chromatogr A. 2015. PMID: 25818558

3

Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion-reversed phase two dimensional-liquid chromatography.

Li Y, Stella C, Zheng L, Bechtel C, Gruenhagen J, Jacobson F, Medley CD. Li Y, et al. Among authors: gruenhagen j. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 1;1032:112-118. doi: 10.1016/j.jchromb.2016.05.011. Epub 2016 May 10. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27212187

4

Antibody-drug conjugate characterization by chromatographic and electrophoretic techniques.

Chen T, Chen Y, Stella C, Medley CD, Gruenhagen JA, Zhang K. Chen T, et al. Among authors: gruenhagen ja. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 1;1032:39-50. doi: 10.1016/j.jchromb.2016.07.023. Epub 2016 Jul 14. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27451254 Review.

5

Spectroscopy-Based Local Modeling Method for High-Throughput Quantification of Nucleic Acid Loading in Lipid Nanoparticles.

Fan Y, Shi Z, Ma S, Razvi SZA, Fu Y, Chen T, Gruenhagen J, Zhang K. Fan Y, et al. Among authors: gruenhagen j. Anal Chem. 2022 Jun 28;94(25):9081-9090. doi: 10.1021/acs.analchem.2c01346. Epub 2022 Jun 14. Anal Chem. 2022. PMID: 35700415

6

Automated online deconjugation of antibody-drug conjugate for small molecule drug profiling.

Thomas R, Song D, Pourmohamad T, Kurita K, Chin S, Dai L, Goyon A, Medley CD, Gruenhagen JA, Chen T. Thomas R, et al. Among authors: gruenhagen ja. J Chromatogr A. 2024 Jan 25;1715:464575. doi: 10.1016/j.chroma.2023.464575. Epub 2023 Dec 17. J Chromatogr A. 2024. PMID: 38150875

7

Development of an advanced separation and characterization platform for mRNA and lipid nanoparticles using multi-detector asymmetrical flow field-flow fractionation.

Gao Z, Lin J, Su WC, Zhang K, Gruenhagen J, Zhong W, Fan Y, Bian J. Gao Z, et al. Among authors: gruenhagen j. Anal Bioanal Chem. 2024 Oct;416(24):5281-5293. doi: 10.1007/s00216-024-05455-x. Epub 2024 Aug 5. Anal Bioanal Chem. 2024. PMID: 39102094

8

Quantification of residual solvents in antibody drug conjugates using gas chromatography.

Medley CD, Kay J, Li Y, Gruenhagen J, Yehl P, Chetwyn NP. Medley CD, et al. Among authors: gruenhagen j. Anal Chim Acta. 2014 Nov 19;850:92-6. doi: 10.1016/j.aca.2014.09.003. Epub 2014 Sep 8. Anal Chim Acta. 2014. PMID: 25441165

9

Simultaneous quantitation of water and residual solvents in pharmaceuticals by rapid headspace gas chromatography with thermal conductivity detection (GC-TCD).

Kay J, Thomas R, Gruenhagen J, Venkatramani CJ. Kay J, et al. Among authors: gruenhagen j. J Pharm Biomed Anal. 2021 Feb 5;194:113796. doi: 10.1016/j.jpba.2020.113796. Epub 2020 Nov 25. J Pharm Biomed Anal. 2021. PMID: 33288344

10

Multiplexed small molecule impurity monitoring in antibody-based therapeutics by mixed-mode chromatography paired with charged aerosol detection.

Chin S, Lin XX, Santarra B, Gruenhagen JA, Yehl P, Chen T. Chin S, et al. Among authors: gruenhagen ja. J Pharm Biomed Anal. 2021 Apr 15;197:113952. doi: 10.1016/j.jpba.2021.113952. Epub 2021 Feb 4. J Pharm Biomed Anal. 2021. PMID: 33601156

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