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Page 1
mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease.
Wege AK, Rom-Jurek EM, Jank P, Denkert C, Ugocsai P, Solbach C, Blohmer JU, Sinn B, van Mackelenbergh M, Möbus V, Trumpp A, Marangoni E, Pfarr N, Irlbeck C, Warfsmann J, Polzer B, Weber F, Ortmann O, Loibl S, Vladimirova V, Brockhoff G. Wege AK, et al. Among authors: warfsmann j. Int J Cancer. 2022 Apr 15;150(8):1357-1372. doi: 10.1002/ijc.33911. Epub 2021 Dec 28. Int J Cancer. 2022. PMID: 34927257
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency.
Werner-Klein M, Grujovic A, Irlbeck C, Obradović M, Hoffmann M, Koerkel-Qu H, Lu X, Treitschke S, Köstler C, Botteron C, Weidele K, Werno C, Polzer B, Kirsch S, Gužvić M, Warfsmann J, Honarnejad K, Czyz Z, Feliciello G, Blochberger I, Grunewald S, Schneider E, Haunschild G, Patwary N, Guetter S, Huber S, Rack B, Harbeck N, Buchholz S, Rümmele P, Heine N, Rose-John S, Klein CA. Werner-Klein M, et al. Among authors: warfsmann j. Nat Commun. 2020 Oct 5;11(1):4977. doi: 10.1038/s41467-020-18701-4. Nat Commun. 2020. PMID: 33020483 Free PMC article.
Tenomodulin knockout mice exhibit worse late healing outcomes with augmented trauma-induced heterotopic ossification of Achilles tendon.
Delgado Caceres M, Angerpointner K, Galler M, Lin D, Michel PA, Brochhausen C, Lu X, Varadarajan AR, Warfsmann J, Stange R, Alt V, Pfeifer CG, Docheva D. Delgado Caceres M, et al. Among authors: warfsmann j. Cell Death Dis. 2021 Nov 5;12(11):1049. doi: 10.1038/s41419-021-04298-z. Cell Death Dis. 2021. PMID: 34741033 Free PMC article.
The Medicago genome provides insight into the evolution of rhizobial symbioses.
Young ND, Debellé F, Oldroyd GE, Geurts R, Cannon SB, Udvardi MK, Benedito VA, Mayer KF, Gouzy J, Schoof H, Van de Peer Y, Proost S, Cook DR, Meyers BC, Spannagl M, Cheung F, De Mita S, Krishnakumar V, Gundlach H, Zhou S, Mudge J, Bharti AK, Murray JD, Naoumkina MA, Rosen B, Silverstein KA, Tang H, Rombauts S, Zhao PX, Zhou P, Barbe V, Bardou P, Bechner M, Bellec A, Berger A, Bergès H, Bidwell S, Bisseling T, Choisne N, Couloux A, Denny R, Deshpande S, Dai X, Doyle JJ, Dudez AM, Farmer AD, Fouteau S, Franken C, Gibelin C, Gish J, Goldstein S, González AJ, Green PJ, Hallab A, Hartog M, Hua A, Humphray SJ, Jeong DH, Jing Y, Jöcker A, Kenton SM, Kim DJ, Klee K, Lai H, Lang C, Lin S, Macmil SL, Magdelenat G, Matthews L, McCorrison J, Monaghan EL, Mun JH, Najar FZ, Nicholson C, Noirot C, O'Bleness M, Paule CR, Poulain J, Prion F, Qin B, Qu C, Retzel EF, Riddle C, Sallet E, Samain S, Samson N, Sanders I, Saurat O, Scarpelli C, Schiex T, Segurens B, Severin AJ, Sherrier DJ, Shi R, Sims S, Singer SR, Sinharoy S, Sterck L, Viollet A, Wang BB, Wang K, Wang M, Wang X, Warfsmann J, Weissenbach J, White DD, White JD, Wiley GB, Wincker P, Xing Y, Yang L, Yao Z, Ying F, Zhai J, Zhou L, Zu… See abstract for full author list ➔ Young ND, et al. Among authors: warfsmann j. Nature. 2011 Nov 16;480(7378):520-4. doi: 10.1038/nature10625. Nature. 2011. PMID: 22089132 Free PMC article.
Dormancy-inducing 3D engineered matrix uncovers mechanosensitive and drug-protective FHL2-p21 signaling axis.
Bakhshandeh S, Heras U, Taïeb HM, Varadarajan AR, Lissek SM, Hücker SM, Lu X, Garske DS, Young SAE, Abaurrea A, Caffarel MM, Riestra A, Bragado P, Contzen J, Gossen M, Kirsch S, Warfsmann J, Honarnejad K, Klein CA, Cipitria A. Bakhshandeh S, et al. Among authors: warfsmann j. Sci Adv. 2024 Nov 8;10(45):eadr3997. doi: 10.1126/sciadv.adr3997. Epub 2024 Nov 6. Sci Adv. 2024. PMID: 39504377 Free PMC article.
Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients.
Stojanović Gužvić N, Lüke F, Treitschke S, Coluccio A, Hoffmann M, Feliciello G, Varadarajan AR, Lu X, Weidele K, Botteron C, Materna-Reichelt S, Keil F, Evert K, Weber F, Schamberger T, Althammer M, Grosse J, Hellwig D, Schulz C, Seitz S, Ugocsai P, Schlenska-Lange A, Mayr R, Kaiser U, Dietmaier W, Polzer B, Warfsmann J, Honarnejad K, Pukrop T, Heudobler D, Klein CA, Werno C. Stojanović Gužvić N, et al. Among authors: warfsmann j. Mol Oncol. 2024 Oct 5. doi: 10.1002/1878-0261.13741. Online ahead of print. Mol Oncol. 2024. PMID: 39367702 Free article.
Ex vivo expansion of lung cancer-derived disseminated cancer cells from lymph nodes identifies cells associated with metastatic progression.
Treitschke S, Weidele K, Varadarajan AR, Feliciello G, Warfsmann J, Vorbeck S, Polzer B, Botteron C, Hoffmann M, Dechand V, Mederer T, Weber F, Werner-Klein M, Robold T, Hofmann HS, Werno C, Klein CA. Treitschke S, et al. Among authors: warfsmann j. Int J Cancer. 2023 Nov 15;153(10):1854-1867. doi: 10.1002/ijc.34658. Epub 2023 Aug 9. Int J Cancer. 2023. PMID: 37555668
Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value.
Franken A, Kraemer A, Sicking A, Watolla M, Rivandi M, Yang L, Warfsmann J, Polzer BM, Friedl TWP, Meier-Stiegen F, Stoecklein NH, Dayan D, Riethdorf S, Mueller V, Pantel K, Koch A, Hartkopf AD, Krawczyk N, Ruckhaeberle E, Niederacher D, Fehm T, Neubauer H. Franken A, et al. Among authors: warfsmann j. Br J Cancer. 2023 May;128(9):1742-1752. doi: 10.1038/s41416-023-02179-0. Epub 2023 Feb 23. Br J Cancer. 2023. PMID: 36823365 Free PMC article.
Facing the large variety of life-limiting conditions in children.
Hoell JI, Weber H, Warfsmann J, Trocan L, Gagnon G, Danneberg M, Balzer S, Keller T, Janßen G, Kuhlen M. Hoell JI, et al. Among authors: warfsmann j. Eur J Pediatr. 2019 Dec;178(12):1893-1902. doi: 10.1007/s00431-019-03467-9. Epub 2019 Oct 17. Eur J Pediatr. 2019. PMID: 31624947
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