Wege AK - Search Results

1

mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease.

Wege AK, Rom-Jurek EM, Jank P, Denkert C, Ugocsai P, Solbach C, Blohmer JU, Sinn B, van Mackelenbergh M, Möbus V, Trumpp A, Marangoni E, Pfarr N, Irlbeck C, Warfsmann J, Polzer B, Weber F, Ortmann O, Loibl S, Vladimirova V, Brockhoff G. Wege AK, et al. Int J Cancer. 2022 Apr 15;150(8):1357-1372. doi: 10.1002/ijc.33911. Epub 2021 Dec 28. Int J Cancer. 2022. PMID: 34927257

2

Multichromatic phenotyping of HER receptor coexpression in breast tumor tissue samples using flow cytometry--possibilities and limitations.

Vollmann-Zwerenz A, Diermeier-Daucher S, Wege AK, Sassen A, Schmidt-Brücken E, Hofstaedter F, Ortmann O, Nauwelaers F, Brockhoff G. Vollmann-Zwerenz A, et al. Among authors: wege ak. Cytometry A. 2010 Apr;77(4):387-98. doi: 10.1002/cyto.a.20868. Cytometry A. 2010. PMID: 20151455 Free article.

3

Humanized tumor mice--a new model to study and manipulate the immune response in advanced cancer therapy.

Wege AK, Ernst W, Eckl J, Frankenberger B, Vollmann-Zwerenz A, Männel DN, Ortmann O, Kroemer A, Brockhoff G. Wege AK, et al. Int J Cancer. 2011 Nov 1;129(9):2194-206. doi: 10.1002/ijc.26159. Epub 2011 Jul 21. Int J Cancer. 2011. PMID: 21544806

4

High resolution ultrasound including elastography and contrast-enhanced ultrasound (CEUS) for early detection and characterization of liver lesions in the humanized tumor mouse model.

Wege AK, Schardt K, Schaefer S, Kroemer A, Brockhoff G, Jung EM. Wege AK, et al. Clin Hemorheol Microcirc. 2012;52(2-4):93-106. doi: 10.3233/CH-2012-1587. Clin Hemorheol Microcirc. 2012. PMID: 22975935

5

Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies.

Wege AK, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, Lehmann J. Wege AK, et al. MAbs. 2014 Jul-Aug;6(4):968-77. doi: 10.4161/mabs.29111. Epub 2014 May 8. MAbs. 2014. PMID: 24870377 Free PMC article.

6

Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity.

Huber S, Wege AK, Bernhardt G, Buschauer A, Brockhoff G. Huber S, et al. Among authors: wege ak. Cytometry A. 2015 Aug;87(8):707-16. doi: 10.1002/cyto.a.22675. Epub 2015 Apr 17. Cytometry A. 2015. PMID: 25892097 Free article.

7

IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM).

Wege AK, Weber F, Kroemer A, Ortmann O, Nimmerjahn F, Brockhoff G. Wege AK, et al. Oncotarget. 2017 Jan 10;8(2):2731-2744. doi: 10.18632/oncotarget.13159. Oncotarget. 2017. PMID: 27835865 Free PMC article.

8

Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice.

Rom-Jurek EM, Kirchhammer N, Ugocsai P, Ortmann O, Wege AK, Brockhoff G. Rom-Jurek EM, et al. Among authors: wege ak. Int J Mol Sci. 2018 Feb 13;19(2):563. doi: 10.3390/ijms19020563. Int J Mol Sci. 2018. PMID: 29438316 Free PMC article.

9

The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease.

Brockhoff G, Seitz S, Weber F, Zeman F, Klinkhammer-Schalke M, Ortmann O, Wege AK. Brockhoff G, et al. Among authors: wege ak. Oncotarget. 2017 Dec 27;9(5):6201-6212. doi: 10.18632/oncotarget.23717. eCollection 2018 Jan 19. Oncotarget. 2017. PMID: 29464065 Free PMC article.

10

HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women.

Wege AK, Chittka D, Buchholz S, Klinkhammer-Schalke M, Diermeier-Daucher S, Zeman F, Ortmann O, Brockhoff G. Wege AK, et al. Breast Cancer Res. 2018 Nov 20;20(1):139. doi: 10.1186/s13058-018-1072-1. Breast Cancer Res. 2018. PMID: 30458882 Free PMC article.

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