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Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier.
Koehler S, Odenthal J, Ludwig V, Unnersjö Jess D, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT. Koehler S, et al. Among authors: janku jl. Kidney Int. 2022 Apr;101(4):733-751. doi: 10.1016/j.kint.2021.11.030. Epub 2021 Dec 17. Kidney Int. 2022. PMID: 34929254