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Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier.
Koehler S, Odenthal J, Ludwig V, Unnersjö Jess D, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT. Koehler S, et al. Among authors: schermer b. Kidney Int. 2022 Apr;101(4):733-751. doi: 10.1016/j.kint.2021.11.030. Epub 2021 Dec 17. Kidney Int. 2022. PMID: 34929254
14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity.
Benzing T, Yaffe MB, Arnould T, Sellin L, Schermer B, Schilling B, Schreiber R, Kunzelmann K, Leparc GG, Kim E, Walz G. Benzing T, et al. Among authors: schermer b. J Biol Chem. 2000 Sep 8;275(36):28167-72. doi: 10.1074/jbc.M002905200. J Biol Chem. 2000. PMID: 10862767 Free article.
We have recently shown that RGS proteins may be regulated on a post-translational level (Benzing, T., Brandes, R., Sellin, L., Schermer, B., Lecker, S., Walz, G., and Kim, E. (1999) Nat. Med. 5, 913-918). However, mechanisms controlling the GAP activity of RGS prote …
We have recently shown that RGS proteins may be regulated on a post-translational level (Benzing, T., Brandes, R., Sellin, L., Schermer …
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.
Köttgen M, Benzing T, Simmen T, Tauber R, Buchholz B, Feliciangeli S, Huber TB, Schermer B, Kramer-Zucker A, Höpker K, Simmen KC, Tschucke CC, Sandford R, Kim E, Thomas G, Walz G. Köttgen M, et al. Among authors: schermer b. EMBO J. 2005 Feb 23;24(4):705-16. doi: 10.1038/sj.emboj.7600566. Epub 2005 Feb 3. EMBO J. 2005. PMID: 15692563 Free PMC article.
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.
Huber TB, Schermer B, Müller RU, Höhne M, Bartram M, Calixto A, Hagmann H, Reinhardt C, Koos F, Kunzelmann K, Shirokova E, Krautwurst D, Harteneck C, Simons M, Pavenstädt H, Kerjaschki D, Thiele C, Walz G, Chalfie M, Benzing T. Huber TB, et al. Among authors: schermer b. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17079-86. doi: 10.1073/pnas.0607465103. Epub 2006 Nov 1. Proc Natl Acad Sci U S A. 2006. PMID: 17079490 Free PMC article.
156 results