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Page 1
Durable antitumor responses to CD47 blockade require adaptive immune stimulation.
Sockolosky JT, Dougan M, Ingram JR, Ho CC, Kauke MJ, Almo SC, Ploegh HL, Garcia KC. Sockolosky JT, et al. Among authors: garcia kc. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2646-54. doi: 10.1073/pnas.1604268113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091975 Free PMC article.
Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.
Ho CCM, Chhabra A, Starkl P, Schnorr PJ, Wilmes S, Moraga I, Kwon HS, Gaudenzio N, Sibilano R, Wehrman TS, Gakovic M, Sockolosky JT, Tiffany MR, Ring AM, Piehler J, Weissman IL, Galli SJ, Shizuru JA, Garcia KC. Ho CCM, et al. Among authors: garcia kc. Cell. 2017 Mar 9;168(6):1041-1052.e18. doi: 10.1016/j.cell.2017.02.011. Cell. 2017. PMID: 28283060 Free PMC article.
Localized CD47 blockade enhances immunotherapy for murine melanoma.
Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M. Ingram JR, et al. Among authors: garcia kc. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10184-10189. doi: 10.1073/pnas.1710776114. Epub 2017 Sep 5. Proc Natl Acad Sci U S A. 2017. PMID: 28874561 Free PMC article.
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.
Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC. Sockolosky JT, et al. Among authors: garcia kc. Science. 2018 Mar 2;359(6379):1037-1042. doi: 10.1126/science.aar3246. Science. 2018. PMID: 29496879 Free PMC article.
Structure of the IFNγ receptor complex guides design of biased agonists.
Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC. Mendoza JL, et al. Among authors: garcia kc. Nature. 2019 Mar;567(7746):56-60. doi: 10.1038/s41586-019-0988-7. Epub 2019 Feb 27. Nature. 2019. PMID: 30814731 Free PMC article.
306 results