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Page 1
Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension.
Mc Crudden MTC, Larrañeta E, Clark A, Jarrahian C, Rein-Weston A, Lachau-Durand S, Niemeijer N, Williams P, Haeck C, McCarthy HO, Zehrung D, Donnelly RF. Mc Crudden MTC, et al. Among authors: lachau durand s. J Control Release. 2018 Dec 28;292:119-129. doi: 10.1016/j.jconrel.2018.11.002. Epub 2018 Nov 2. J Control Release. 2018. PMID: 30395897 Free PMC article.
Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi.
Fischer C, Ibiricu Urriza I, Bulman CA, Lim KC, Gut J, Lachau-Durand S, Engelen M, Quirynen L, Tekle F, Baeten B, Beerntsen B, Lustigman S, Sakanari J. Fischer C, et al. Among authors: lachau durand s. PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0006787. doi: 10.1371/journal.pntd.0006787. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30650084 Free PMC article.
Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds.
Hübner MP, Ehrens A, Koschel M, Dubben B, Lenz F, Frohberger SJ, Specht S, Quirynen L, Lachau-Durand S, Tekle F, Baeten B, Engelen M, Mackenzie CD, Hoerauf A. Hübner MP, et al. Among authors: lachau durand s. PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0006320. doi: 10.1371/journal.pntd.0006320. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30650105 Free PMC article.
Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery.
Mc Crudden MTC, Larrañeta E, Clark A, Jarrahian C, Rein-Weston A, Creelman B, Moyo Y, Lachau-Durand S, Niemeijer N, Williams P, McCarthy HO, Zehrung D, Donnelly RF. Mc Crudden MTC, et al. Among authors: lachau durand s. Adv Healthc Mater. 2019 May;8(9):e1801510. doi: 10.1002/adhm.201801510. Epub 2019 Mar 6. Adv Healthc Mater. 2019. PMID: 30838804
Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Berke JM, Vijgen L, Lachau-Durand S, Powdrill MH, Rawe S, Sjuvarsson E, Eriksson S, Götte M, Fransen E, Dehertogh P, Van den Eynde C, Leclercq L, Jonckers TH, Raboisson P, Nilsson M, Samuelsson B, Rosenquist Å, Fanning GC, Lin TI. Berke JM, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3812-20. doi: 10.1128/AAC.00214-11. Epub 2011 May 16. Antimicrob Agents Chemother. 2011. PMID: 21576430 Free PMC article.
Discovery of 1-((2R,4aR,6R,7R,7aR)-2-Isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2'-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione (JNJ-54257099), a 3'-5'-Cyclic Phosphate Ester Prodrug of 2'-Deoxy-2'-Spirooxetane Uridine Triphosphate Useful for HCV Inhibition.
Jonckers TH, Tahri A, Vijgen L, Berke JM, Lachau-Durand S, Stoops B, Snoeys J, Leclercq L, Tambuyzer L, Lin TI, Simmen K, Raboisson P. Jonckers TH, et al. J Med Chem. 2016 Jun 23;59(12):5790-8. doi: 10.1021/acs.jmedchem.6b00382. Epub 2016 Jun 3. J Med Chem. 2016. PMID: 27181575
Evaluation of Three Amorphous Drug Delivery Technologies to Improve the Oral Absorption of Flubendazole.
Vialpando M, Smulders S, Bone S, Jager C, Vodak D, Van Speybroeck M, Verheyen L, Backx K, Boeykens P, Brewster ME, Ceulemans J, Novoa de Armas H, Van Geel K, Kesselaers E, Hillewaert V, Lachau-Durand S, Meurs G, Psathas P, Van Hove B, Verreck G, Voets M, Weuts I, Mackie C. Vialpando M, et al. J Pharm Sci. 2016 Sep;105(9):2782-2793. doi: 10.1016/j.xphs.2016.03.003. Epub 2016 Apr 22. J Pharm Sci. 2016. PMID: 27113473 Free PMC article.
19 results