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Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease.
Beltran WA, Cideciyan AV, Iwabe S, Swider M, Kosyk MS, McDaid K, Martynyuk I, Ying GS, Shaffer J, Deng WT, Boye SL, Lewin AS, Hauswirth WW, Jacobson SG, Aguirre GD. Beltran WA, et al. Among authors: ying gs. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5844-53. doi: 10.1073/pnas.1509914112. Epub 2015 Oct 12. Proc Natl Acad Sci U S A. 2015. PMID: 26460017 Free PMC article.
Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations.
Beltran WA, Cideciyan AV, Boye SE, Ye GJ, Iwabe S, Dufour VL, Marinho LF, Swider M, Kosyk MS, Sha J, Boye SL, Peterson JJ, Witherspoon CD, Alexander JJ, Ying GS, Shearman MS, Chulay JD, Hauswirth WW, Gamlin PD, Jacobson SG, Aguirre GD. Beltran WA, et al. Among authors: ying gs. Mol Ther. 2017 Aug 2;25(8):1866-1880. doi: 10.1016/j.ymthe.2017.05.004. Epub 2017 May 27. Mol Ther. 2017. PMID: 28566226 Free PMC article.
Toxicity and Efficacy Evaluation of an Adeno-Associated Virus Vector Expressing Codon-Optimized RPGR Delivered by Subretinal Injection in a Canine Model of X-linked Retinitis Pigmentosa.
Dufour VL, Cideciyan AV, Ye GJ, Song C, Timmers A, Habecker PL, Pan W, Weinstein NM, Swider M, Durham AC, Ying GS, Robinson PM, Jacobson SG, Knop DR, Chulay JD, Shearman MS, Aguirre GD, Beltran WA. Dufour VL, et al. Among authors: ying gs. Hum Gene Ther. 2020 Feb;31(3-4):253-267. doi: 10.1089/hum.2019.297. Epub 2020 Feb 6. Hum Gene Ther. 2020. PMID: 31910043 Free PMC article.
Association of Dry Eye Symptoms and Signs in Patients with Dry Eye Disease.
Tawfik A, Pistilli M, Maguire MG, Chen Y, Yu Y, Greiner JV, Asbell PA, Ying GS; Dry Eye Assessment and Management (DREAM) Study Research Group. Tawfik A, et al. Among authors: ying gs. Ophthalmic Epidemiol. 2024 Jun;31(3):274-282. doi: 10.1080/09286586.2023.2248629. Epub 2023 Aug 17. Ophthalmic Epidemiol. 2024. PMID: 37592829
455 results