Bushman FD - Search Results

1

Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial.

Boulad F, Maggio A, Wang X, Moi P, Acuto S, Kogel F, Takpradit C, Prockop S, Mansilla-Soto J, Cabriolu A, Odak A, Qu J, Thummar K, Du F, Shen L, Raso S, Barone R, Di Maggio R, Pitrolo L, Giambona A, Mingoia M, Everett JK, Hokama P, Roche AM, Cantu VA, Adhikari H, Reddy S, Bouhassira E, Mohandas N, Bushman FD, Rivière I, Sadelain M. Boulad F, et al. Among authors: bushman fd. Nat Med. 2022 Jan;28(1):63-70. doi: 10.1038/s41591-021-01554-9. Epub 2022 Jan 3. Nat Med. 2022. PMID: 34980909 Free PMC article. Clinical Trial.

2

Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells.

Wang GP, Levine BL, Binder GK, Berry CC, Malani N, McGarrity G, Tebas P, June CH, Bushman FD. Wang GP, et al. Among authors: bushman fd. Mol Ther. 2009 May;17(5):844-50. doi: 10.1038/mt.2009.16. Epub 2009 Mar 3. Mol Ther. 2009. PMID: 19259065 Free PMC article.

3

Dynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trial.

Wang GP, Berry CC, Malani N, Leboulch P, Fischer A, Hacein-Bey-Abina S, Cavazzana-Calvo M, Bushman FD. Wang GP, et al. Among authors: bushman fd. Blood. 2010 Jun 3;115(22):4356-66. doi: 10.1182/blood-2009-12-257352. Epub 2010 Mar 12. Blood. 2010. PMID: 20228274 Free PMC article. Clinical Trial.

4

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells.

Papapetrou EP, Lee G, Malani N, Setty M, Riviere I, Tirunagari LM, Kadota K, Roth SL, Giardina P, Viale A, Leslie C, Bushman FD, Studer L, Sadelain M. Papapetrou EP, et al. Among authors: bushman fd. Nat Biotechnol. 2011 Jan;29(1):73-8. doi: 10.1038/nbt.1717. Epub 2010 Dec 12. Nat Biotechnol. 2011. PMID: 21151124 Free PMC article.

5

Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.

Ronen K, Negre O, Roth S, Colomb C, Malani N, Denaro M, Brady T, Fusil F, Gillet-Legrand B, Hehir K, Beuzard Y, Leboulch P, Down JD, Payen E, Bushman FD. Ronen K, et al. Among authors: bushman fd. Mol Ther. 2011 Jul;19(7):1273-86. doi: 10.1038/mt.2011.20. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386821 Free PMC article.

6

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy.

Brady T, Roth SL, Malani N, Wang GP, Berry CC, Leboulch P, Hacein-Bey-Abina S, Cavazzana-Calvo M, Papapetrou EP, Sadelain M, Savilahti H, Bushman FD. Brady T, et al. Among authors: bushman fd. Nucleic Acids Res. 2011 Jun;39(11):e72. doi: 10.1093/nar/gkr140. Epub 2011 Mar 16. Nucleic Acids Res. 2011. PMID: 21415009 Free PMC article.

7

Safe harbours for the integration of new DNA in the human genome.

Sadelain M, Papapetrou EP, Bushman FD. Sadelain M, et al. Among authors: bushman fd. Nat Rev Cancer. 2011 Dec 1;12(1):51-8. doi: 10.1038/nrc3179. Nat Rev Cancer. 2011. PMID: 22129804 Review.

8

Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation.

Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, Larosa DF, Renner ED, Orange JS, Bushman FD, Artis D. Hill DA, et al. Among authors: bushman fd. Nat Med. 2012 Mar 25;18(4):538-46. doi: 10.1038/nm.2657. Nat Med. 2012. PMID: 22447074 Free PMC article.

9

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.

Tebas P, Stein D, Binder-Scholl G, Mukherjee R, Brady T, Rebello T, Humeau L, Kalos M, Papasavvas E, Montaner LJ, Schullery D, Shaheen F, Brennan AL, Zheng Z, Cotte J, Slepushkin V, Veloso E, Mackley A, Hwang WT, Aberra F, Zhan J, Boyer J, Collman RG, Bushman FD, Levine BL, June CH. Tebas P, et al. Among authors: bushman fd. Blood. 2013 Feb 28;121(9):1524-33. doi: 10.1182/blood-2012-07-447250. Epub 2012 Dec 20. Blood. 2013. PMID: 23264589 Free PMC article. Clinical Trial.

10

Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis.

Hergott CB, Roche AM, Tamashiro E, Clarke TB, Bailey AG, Laughlin A, Bushman FD, Weiser JN. Hergott CB, et al. Among authors: bushman fd. Blood. 2016 May 19;127(20):2460-71. doi: 10.1182/blood-2015-10-675173. Epub 2016 Mar 17. Blood. 2016. PMID: 26989200 Free PMC article.

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