Melki R - Search Results

1

Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells.

Vasili E, Dominguez-Meijide A, Flores-León M, Al-Azzani M, Kanellidi A, Melki R, Stefanis L, Outeiro TF. Vasili E, et al. Among authors: melki r. Mol Neurobiol. 2022 Feb;59(2):1273-1284. doi: 10.1007/s12035-021-02713-2. Epub 2022 Jan 4. Mol Neurobiol. 2022. PMID: 34984585 Free PMC article.

2

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.

Hansen C, Angot E, Bergström AL, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li JY, Brundin P. Hansen C, et al. Among authors: melki r. J Clin Invest. 2011 Feb;121(2):715-25. doi: 10.1172/JCI43366. Epub 2011 Jan 18. J Clin Invest. 2011. PMID: 21245577 Free PMC article.

3

Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.

Diepenbroek M, Casadei N, Esmer H, Saido TC, Takano J, Kahle PJ, Nixon RA, Rao MV, Melki R, Pieri L, Helling S, Marcus K, Krueger R, Masliah E, Riess O, Nuber S. Diepenbroek M, et al. Among authors: melki r. Hum Mol Genet. 2014 Aug 1;23(15):3975-89. doi: 10.1093/hmg/ddu112. Epub 2014 Mar 11. Hum Mol Genet. 2014. PMID: 24619358 Free PMC article.

4

Alpha-synuclein and the prion hypothesis in Parkinson's disease.

Melki R. Melki R. Rev Neurol (Paris). 2018 Nov;174(9):644-652. doi: 10.1016/j.neurol.2018.08.002. Epub 2018 Sep 7. Rev Neurol (Paris). 2018. PMID: 30201422 Review.

5

Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network.

Gribaudo S, Tixador P, Bousset L, Fenyi A, Lino P, Melki R, Peyrin JM, Perrier AL. Gribaudo S, et al. Among authors: melki r. Stem Cell Reports. 2019 Feb 12;12(2):230-244. doi: 10.1016/j.stemcr.2018.12.007. Epub 2019 Jan 10. Stem Cell Reports. 2019. PMID: 30639210 Free PMC article.

6

Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration.

Peralta Ramos JM, Iribarren P, Bousset L, Melki R, Baekelandt V, Van der Perren A. Peralta Ramos JM, et al. Among authors: melki r. Front Immunol. 2019 Jan 29;10:80. doi: 10.3389/fimmu.2019.00080. eCollection 2019. Front Immunol. 2019. PMID: 30761145 Free PMC article.

7

Detection of alpha-synuclein aggregates in gastrointestinal biopsies by protein misfolding cyclic amplification.

Fenyi A, Leclair-Visonneau L, Clairembault T, Coron E, Neunlist M, Melki R, Derkinderen P, Bousset L. Fenyi A, et al. Among authors: melki r. Neurobiol Dis. 2019 Sep;129:38-43. doi: 10.1016/j.nbd.2019.05.002. Epub 2019 May 9. Neurobiol Dis. 2019. PMID: 31078683 Free article.

8

α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities.

Alam P, Bousset L, Melki R, Otzen DE. Alam P, et al. Among authors: melki r. J Neurochem. 2019 Sep;150(5):522-534. doi: 10.1111/jnc.14808. Epub 2019 Aug 2. J Neurochem. 2019. PMID: 31254394 Free article. Review.

9

Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease.

Grozdanov V, Bousset L, Hoffmeister M, Bliederhaeuser C, Meier C, Madiona K, Pieri L, Kiechle M, McLean PJ, Kassubek J, Behrends C, Ludolph AC, Weishaupt JH, Melki R, Danzer KM. Grozdanov V, et al. Among authors: melki r. Ann Neurol. 2019 Oct;86(4):593-606. doi: 10.1002/ana.25557. Epub 2019 Aug 15. Ann Neurol. 2019. PMID: 31343083

10

Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP⁺-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons.

Kawahata I, Bousset L, Melki R, Fukunaga K. Kawahata I, et al. Among authors: melki r. Int J Mol Sci. 2019 Oct 28;20(21):5358. doi: 10.3390/ijms20215358. Int J Mol Sci. 2019. PMID: 31661838 Free PMC article.

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