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Glutamate in primary afferents is required for itch transmission.
Cui L, Guo J, Cranfill SL, Gautam M, Bhattarai J, Olson W, Beattie K, Challis RC, Wu Q, Song X, Raabe T, Gradinaru V, Ma M, Liu Q, Luo W. Cui L, et al. Among authors: liu q. Neuron. 2022 Mar 2;110(5):809-823.e5. doi: 10.1016/j.neuron.2021.12.007. Epub 2022 Jan 4. Neuron. 2022. PMID: 34986325 Free PMC article.
TRPC3 Is Dispensable for β-Alanine Triggered Acute Itch.
Dong P, Guo C, Huang S, Ma M, Liu Q, Luo W. Dong P, et al. Among authors: liu q. Sci Rep. 2017 Oct 24;7(1):13869. doi: 10.1038/s41598-017-12770-0. Sci Rep. 2017. PMID: 29066740 Free PMC article.
TRPC3 Antagonizes Pruritus in a Mouse Contact Dermatitis Model.
Beattie K, Jiang H, Gautam M, MacVittie MK, Miller B, Ma M, Liu Q, Luo W. Beattie K, et al. Among authors: liu q. J Invest Dermatol. 2022 Apr;142(4):1136-1144. doi: 10.1016/j.jid.2021.08.433. Epub 2021 Sep 25. J Invest Dermatol. 2022. PMID: 34570999 Free PMC article.
A histamine-independent itch pathway is required for allergic ocular itch.
Huang CC, Kim YS, Olson WP, Li F, Guo C, Luo W, Huang AJW, Liu Q. Huang CC, et al. Among authors: liu q. J Allergy Clin Immunol. 2016 Apr;137(4):1267-1270.e6. doi: 10.1016/j.jaci.2015.08.047. Epub 2015 Oct 28. J Allergy Clin Immunol. 2016. PMID: 26521042 Free PMC article.
Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem.
Li F, Jiang H, Shen X, Yang W, Guo C, Wang Z, Xiao M, Cui L, Luo W, Kim BS, Chen Z, Huang AJW, Liu Q. Li F, et al. Among authors: liu q. Cell. 2021 Jul 8;184(14):3762-3773.e10. doi: 10.1016/j.cell.2021.05.017. Epub 2021 Jun 15. Cell. 2021. PMID: 34133943 Free PMC article.
Facilitation of MrgprD by TRP-A1 promotes neuropathic pain.
Wang C, Gu L, Ruan Y, Geng X, Xu M, Yang N, Yu L, Jiang Y, Zhu C, Yang Y, Zhou Y, Guan X, Luo W, Liu Q, Dong X, Yu G, Lan L, Tang Z. Wang C, et al. Among authors: liu q. FASEB J. 2019 Jan;33(1):1360-1373. doi: 10.1096/fj.201800615RR. Epub 2018 Aug 27. FASEB J. 2019. PMID: 30148678 Free PMC article.
-Wang, C., Gu, L., Ruan, Y., Geng, X., Xu, M., Yang, N., Yu, L., Jiang, Y., Zhu, C., Yang, Y., Zhou, Y., Guan, X., Luo, W., Liu, Q., Dong, X., Yu, G., Lan, L., Tang, Z. Facilitation of MrgprD by TRP-A1 promotes neuropathic pain....
-Wang, C., Gu, L., Ruan, Y., Geng, X., Xu, M., Yang, N., Yu, L., Jiang, Y., Zhu, C., Yang, Y., Zhou, Y., Guan, X., Luo, W., Liu, Q …
Conopeptides promote itch through human itch receptor hMgprX1.
Espino SS, Robinson SD, Safavi-Hemami H, Gajewiak J, Yang W, Olivera BM, Liu Q. Espino SS, et al. Among authors: liu q. Toxicon. 2018 Nov;154:28-34. doi: 10.1016/j.toxicon.2018.09.002. Epub 2018 Sep 21. Toxicon. 2018. PMID: 30243794 Free PMC article.
The role of the Mrgpr receptor family in itch.
Liu Q, Dong X. Liu Q, et al. Handb Exp Pharmacol. 2015;226:71-88. doi: 10.1007/978-3-662-44605-8_5. Handb Exp Pharmacol. 2015. PMID: 25861775 Review.
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