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Page 1
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick M, Zhang L, Maurer S, Maurer HC, Isaakaidis K, Schneider L, Patra U, Schunck K, Rohleder E, Hofstetter J, Baluapuri A, Scherger AK, Slotta-Huspenina J, Hettler F, Weber J, Engleitner T, Maresch R, Slawska J, Lewis R, Istvanffy R, Habringer S, Steiger K, Baiker A, Oostendorp RAJ, Miething C, Lenhof HP, Bassermann F, Chapuy B, Wirth M, Wolf E, Rad R, Müller S, Keller U. Schick M, et al. Among authors: hettler f. Nat Commun. 2022 Jan 12;13(1):281. doi: 10.1038/s41467-021-27704-8. Nat Commun. 2022. PMID: 35022408 Free PMC article.
Secreted factors from mouse embryonic fibroblasts maintain repopulating function of single cultured hematopoietic stem cells.
Romero Marquez S, Hettler F, Hausinger R, Schreck C, Landspersky T, Henkel L, Angerpointner C, Demir IE, Schiemann M, Bassermann F, Götze KS, Istvánffy R, Oostendorp RAJ. Romero Marquez S, et al. Among authors: hettler f. Haematologica. 2021 Oct 1;106(10):2633-2640. doi: 10.3324/haematol.2020.249102. Haematologica. 2021. PMID: 33543864 Free PMC article.
Cathepsin K maintains the compartment of bone marrow T lymphocytes in vivo.
Hausinger R, Hackl M, Jardon Alvarez A, Kehr M, Romero Marquez S, Hettler F, Kehr C, Grziwok S, Schreck C, Peschel C, Istvánffy R, Oostendorp RAJ. Hausinger R, et al. Among authors: hettler f. Immun Inflamm Dis. 2021 Jun;9(2):521-532. doi: 10.1002/iid3.412. Epub 2021 Feb 16. Immun Inflamm Dis. 2021. PMID: 33592138 Free PMC article.
Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress.
Landspersky T, Saçma M, Rivière J, Hecker JS, Hettler F, Hameister E, Brandstetter K, Istvánffy R, Romero Marquez S, Ludwig R, Götz M, Buck M, Wolf M, Schiemann M, Ruland J, Strunk D, Shimamura A, Myers K, Yamaguchi TP, Kieslinger M, Leonhardt H, Bassermann F, Götze KS, Geiger H, Schreck C, Oostendorp RAJ. Landspersky T, et al. Among authors: hettler f. Blood. 2022 Feb 3;139(5):690-703. doi: 10.1182/blood.2021011775. Blood. 2022. PMID: 34657154 Free PMC article.
Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300.
Hettler F, Schreck C, Marquez SR, Engleitner T, Vilne B, Landspersky T, Weidner H, Hausinger R, Mishra R, Oellinger R, Rauner M, Naumann R, Peschel C, Bassermann F, Rad R, Istvanffy R, Oostendorp RAJ. Hettler F, et al. Haematologica. 2023 Feb 1;108(2):490-501. doi: 10.3324/haematol.2022.280760. Haematologica. 2023. PMID: 35950533 Free PMC article.
Targeting CDC42 reduces skeletal degeneration after hematopoietic stem cell transplantation.
Landspersky T, Stein M, Saçma M, Geuder J, Braitsch K, Rivière J, Hettler F, Romero Marquez S, Vilne B, Hameister E, Richter D, Schönhals E, Tuckermann J, Verbeek M, Herhaus P, Hecker JS, Bassermann F, Götze KS, Enard W, Geiger H, Oostendorp RAJ, Schreck C. Landspersky T, et al. Among authors: hettler f. Blood Adv. 2024 Oct 22;8(20):5400-5414. doi: 10.1182/bloodadvances.2024012879. Blood Adv. 2024. PMID: 39159429 Free PMC article.