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BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy.
Xu X, Chen E, Mo L, Zhang L, Shao F, Miao K, Liu J, Su SM, Valecha M, Chan UI, Zheng H, Chen M, Chen W, Chen Q, Fu H, Aladjem MI, He Y, Deng CX. Xu X, et al. Among authors: chan ui. Hum Mol Genet. 2019 Mar 1;28(5):842-857. doi: 10.1093/hmg/ddy398. Hum Mol Genet. 2019. PMID: 30445628 Free PMC article.
In vivo Mouse Mammary Gland Formation.
Sun H, Zhang X, Chan UI, Su SM, Guo S, Xu X, Deng C. Sun H, et al. Among authors: chan ui. Bio Protoc. 2020 Jul 5;10(13):e3667. doi: 10.21769/BioProtoc.3667. eCollection 2020 Jul 5. Bio Protoc. 2020. PMID: 33659337 Free PMC article.
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform.
Xing F, Liu YC, Huang S, Lyu X, Su SM, Chan UI, Wu PC, Yan Y, Ai N, Li J, Zhao M, Rajendran BK, Liu J, Shao F, Sun H, Choi TK, Zhu W, Luo G, Liu S, Xu L, Chan KL, Zhao Q, Miao K, Luo KQ, Ge W, Xu X, Wang G, Liu TM, Deng CX. Xing F, et al. Among authors: chan ui. Theranostics. 2021 Sep 13;11(19):9415-9430. doi: 10.7150/thno.59533. eCollection 2021. Theranostics. 2021. PMID: 34646378 Free PMC article.
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.
Sun H, Zeng J, Miao Z, Lei KC, Huang C, Hu L, Su SM, Chan UI, Miao K, Zhang X, Zhang A, Guo S, Chen S, Meng Y, Deng M, Hao W, Lei H, Lin Y, Yang Z, Tang D, Wong KH, Zhang XD, Xu X, Deng CX. Sun H, et al. Among authors: chan ui. Theranostics. 2021 Oct 25;11(20):9967-9987. doi: 10.7150/thno.63995. eCollection 2021. Theranostics. 2021. PMID: 34815798 Free PMC article.
S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy.
Li J, Shu X, Xu J, Su SM, Chan UI, Mo L, Liu J, Zhang X, Adhav R, Chen Q, Wang Y, An T, Zhang X, Lyu X, Li X, Lei JH, Miao K, Sun H, Xing F, Zhang A, Deng C, Xu X. Li J, et al. Among authors: chan ui. Nat Commun. 2022 Mar 18;13(1):1481. doi: 10.1038/s41467-022-29151-5. Nat Commun. 2022. PMID: 35304461 Free PMC article.
12 results