Deng CX - Search Results

1

ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine.

Xu J, Su SM, Zhang X, Chan UI, Adhav R, Shu X, Liu J, Li J, Mo L, Wang Y, An T, Lei JH, Miao K, Deng CX, Xu X. Xu J, et al. Among authors: deng cx. J Clin Invest. 2022 Mar 1;132(5):e149473. doi: 10.1172/JCI149473. J Clin Invest. 2022. PMID: 35025764 Free PMC article.

2

Generation and analysis of Brca1 conditional knockout mice.

Deng CX, Xu X. Deng CX, et al. Methods Mol Biol. 2004;280:185-200. doi: 10.1385/1-59259-788-2:185. Methods Mol Biol. 2004. PMID: 15187254

3

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.

Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B, Deng CX. Xu X, et al. Among authors: deng cx. J Clin Invest. 2006 Jul;116(7):1843-52. doi: 10.1172/JCI27282. Epub 2006 Jun 8. J Clin Invest. 2006. PMID: 16767220 Free PMC article.

4

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.

Wang RH, Kim HS, Xiao C, Xu X, Gavrilova O, Deng CX. Wang RH, et al. Among authors: deng cx. J Clin Invest. 2011 Nov;121(11):4477-90. doi: 10.1172/JCI46243. Epub 2011 Oct 3. J Clin Invest. 2011. PMID: 21965330 Free PMC article.

5

Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors.

Vassilopoulos A, Xiao C, Chisholm C, Chen W, Xu X, Lahusen TJ, Bewley C, Deng CX. Vassilopoulos A, et al. Among authors: deng cx. J Biol Chem. 2014 Aug 29;289(35):24202-14. doi: 10.1074/jbc.M114.567552. Epub 2014 Jul 8. J Biol Chem. 2014. PMID: 25006250 Free PMC article.

6

SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firing.

Wang RH, Lahusen TJ, Chen Q, Xu X, Jenkins LM, Leo E, Fu H, Aladjem M, Pommier Y, Appella E, Deng CX. Wang RH, et al. Among authors: deng cx. Int J Biol Sci. 2014 Nov 26;10(10):1193-202. doi: 10.7150/ijbs.11066. eCollection 2014. Int J Biol Sci. 2014. PMID: 25516717 Free PMC article.

7

"DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint.

Masuda T, Xu X, Dimitriadis EK, Lahusen T, Deng CX. Masuda T, et al. Among authors: deng cx. Int J Biol Sci. 2016 Jan 1;12(2):133-43. doi: 10.7150/ijbs.14242. eCollection 2016. Int J Biol Sci. 2016. PMID: 26884712 Free PMC article.

8

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin.

Chisholm CL, Wang H, Wong AH, Vazquez-Ortiz G, Chen W, Xu X, Deng CX. Chisholm CL, et al. Among authors: deng cx. Oncotarget. 2016 Dec 20;7(51):84439-84452. doi: 10.18632/oncotarget.12992. Oncotarget. 2016. PMID: 27806319 Free PMC article.

9

CRISPR-Cas9: from Genome Editing to Cancer Research.

Chen S, Sun H, Miao K, Deng CX. Chen S, et al. Among authors: deng cx. Int J Biol Sci. 2016 Nov 4;12(12):1427-1436. doi: 10.7150/ijbs.17421. eCollection 2016. Int J Biol Sci. 2016. PMID: 27994508 Free PMC article. Review.

10

WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance.

Zheng H, Shao F, Martin S, Xu X, Deng CX. Zheng H, et al. Among authors: deng cx. Sci Rep. 2017 Mar 6;7:43517. doi: 10.1038/srep43517. Sci Rep. 2017. PMID: 28262781 Free PMC article.

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