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Page 1
Asymmetric Cation-Olefin Monocyclization by Engineered Squalene-Hopene Cyclases.
Eichenberger M, Hüppi S, Patsch D, Aeberli N, Berweger R, Dossenbach S, Eichhorn E, Flachsmann F, Hortencio L, Voirol F, Vollenweider S, Bornscheuer UT, Buller R. Eichenberger M, et al. Among authors: patsch d. Angew Chem Int Ed Engl. 2021 Dec 6;60(50):26080-26086. doi: 10.1002/anie.202108037. Epub 2021 Sep 17. Angew Chem Int Ed Engl. 2021. PMID: 34346556 Free PMC article.
Improving Enzyme Fitness with Machine Learning.
Patsch D, Buller R. Patsch D, et al. Chimia (Aarau). 2023 Mar 29;77(3):116-121. doi: 10.2533/chimia.2023.116. Chimia (Aarau). 2023. PMID: 38047813 Free article. Review.
Enriching productive mutational paths accelerates enzyme evolution.
Patsch D, Schwander T, Voss M, Schaub D, Hüppi S, Eichenberger M, Stockinger P, Schelbert L, Giger S, Peccati F, Jiménez-Osés G, Mutný M, Krause A, Bornscheuer UT, Hilvert D, Buller RM. Patsch D, et al. Nat Chem Biol. 2024 Dec;20(12):1662-1669. doi: 10.1038/s41589-024-01712-3. Epub 2024 Sep 11. Nat Chem Biol. 2024. PMID: 39261644 Free PMC article.
A stratified phase I dose escalation trial of hypofractionated radiotherapy followed by ipilimumab in metastatic melanoma: long-term follow-up and final outcomes.
Maity A, Mick R, Rengan R, Mitchell TC, Amaravadi RK, Schuchter LM, Pryma DA, Patsch DM, Maity AP, Minn AJ, Vonderheide RH, Lukens JN. Maity A, et al. Among authors: patsch dm. Oncoimmunology. 2021 Jan 31;10(1):1863631. doi: 10.1080/2162402X.2020.1863631. Oncoimmunology. 2021. PMID: 33643689 Free PMC article. Clinical Trial.
Author Correction: Global diversity and biogeography of bacterial communities in wastewater treatment plants.
Wu L, Ning D, Zhang B, Li Y, Zhang P, Shan X, Zhang Q, Brown MR, Li Z, Van Nostrand JD, Ling F, Xiao N, Zhang Y, Vierheilig J, Wells GF, Yang Y, Deng Y, Tu Q, Wang A; Global Water Microbiome Consortium; Zhang T, He Z, Keller J, Nielsen PH, Alvarez PJJ, Criddle CS, Wagner M, Tiedje JM, He Q, Curtis TP, Stahl DA, Alvarez-Cohen L, Rittmann BE, Wen X, Zhou J. Wu L, et al. Nat Microbiol. 2019 Dec;4(12):2579. doi: 10.1038/s41564-019-0617-0. Nat Microbiol. 2019. PMID: 31728072
Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non-Small Cell Lung Cancer: A Phase 1/2 Trial.
Rengan R, Mick R, Pryma DA, Lin LL, Christodouleas J, Plastaras JP, Simone CB 2nd, Gupta AK, Evans TL, Stevenson JP, Langer CJ, Kucharczuk J, Friedberg J, Lam S, Patsch D, Hahn SM, Maity A. Rengan R, et al. Among authors: patsch d. JAMA Oncol. 2019 Oct 1;5(10):1464-1472. doi: 10.1001/jamaoncol.2019.2095. JAMA Oncol. 2019. PMID: 31436839 Free PMC article.
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