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Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.
Cilenti L, Kyriazis GA, Soundarapandian MM, Stratico V, Yerkes A, Park KM, Sheridan AM, Alnemri ES, Bonventre JV, Zervos AS. Cilenti L, et al. Among authors: kyriazis ga. Am J Physiol Renal Physiol. 2005 Feb;288(2):F371-9. doi: 10.1152/ajprenal.00154.2004. Epub 2004 Sep 28. Am J Physiol Renal Physiol. 2005. PMID: 15454391 Free article.
Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study.
Karimian Azari E, Smith KR, Yi F, Osborne TF, Bizzotto R, Mari A, Pratley RE, Kyriazis GA. Karimian Azari E, et al. Among authors: kyriazis ga. Am J Clin Nutr. 2017 Apr;105(4):1001-1009. doi: 10.3945/ajcn.116.146001. Epub 2017 Mar 1. Am J Clin Nutr. 2017. PMID: 28251932 Free PMC article. Clinical Trial.
T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways.
Smith K, Karimian Azari E, LaMoia TE, Hussain T, Vargova V, Karolyi K, Veldhuis PP, Arnoletti JP, de la Fuente SG, Pratley RE, Osborne TF, Kyriazis GA. Smith K, et al. Among authors: kyriazis ga. Mol Metab. 2018 Nov;17:98-111. doi: 10.1016/j.molmet.2018.08.009. Epub 2018 Aug 27. Mol Metab. 2018. PMID: 30201274 Free PMC article.
High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice.
Serrano J, Smith KR, Crouch AL, Sharma V, Yi F, Vargova V, LaMoia TE, Dupont LM, Serna V, Tang F, Gomes-Dias L, Blakeslee JJ, Hatzakis E, Peterson SN, Anderson M, Pratley RE, Kyriazis GA. Serrano J, et al. Among authors: kyriazis ga. Microbiome. 2021 Jan 12;9(1):11. doi: 10.1186/s40168-020-00976-w. Microbiome. 2021. PMID: 33431052 Free PMC article. Clinical Trial.
The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans.
Serrano J, Seflova J, Park J, Pribadi M, Sanematsu K, Shigemura N, Serna V, Yi F, Mari A, Procko E, Pratley RE, Robia SL, Kyriazis GA. Serrano J, et al. Among authors: kyriazis ga. Mol Metab. 2021 Dec;54:101339. doi: 10.1016/j.molmet.2021.101339. Epub 2021 Sep 9. Mol Metab. 2021. PMID: 34509698 Free PMC article.
44 results