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Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1.
Valencia A, Vergara C, Thio CL, Vince N, Douillard V, Grifoni A, Cox AL, Johnson EO, Kral AH, Goedert JJ, Mangia A, Piazzolla V, Mehta SH, Kirk GD, Kim AY, Lauer GM, Chung RT, Price JC, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Busch MP, Alexander G, Rosen HR, Murphy EL, Wojcik GL, Carrington M, Gourraud PA, Sette A, Thomas DL, Duggal P. Valencia A, et al. Among authors: sette a. Am J Hum Genet. 2022 Feb 3;109(2):299-310. doi: 10.1016/j.ajhg.2022.01.001. Epub 2022 Jan 31. Am J Hum Genet. 2022. PMID: 35090584 Free PMC article.
Cellular immune selection with hepatitis C virus persistence in humans.
Cox AL, Mosbruger T, Mao Q, Liu Z, Wang XH, Yang HC, Sidney J, Sette A, Pardoll D, Thomas DL, Ray SC. Cox AL, et al. Among authors: sette a. J Exp Med. 2005 Jun 6;201(11):1741-52. doi: 10.1084/jem.20050121. J Exp Med. 2005. PMID: 15939790 Free PMC article.
Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Schulze zur Wiesch J, et al. Among authors: sette a. J Immunol. 2005 Sep 15;175(6):3603-13. doi: 10.4049/jimmunol.175.6.3603. J Immunol. 2005. PMID: 16148104
High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection.
Rutebemberwa A, Ray SC, Astemborski J, Levine J, Liu L, Dowd KA, Clute S, Wang C, Korman A, Sette A, Sidney J, Pardoll DM, Cox AL. Rutebemberwa A, et al. Among authors: sette a. J Immunol. 2008 Dec 15;181(12):8215-25. doi: 10.4049/jimmunol.181.12.8215. J Immunol. 2008. PMID: 19050238 Free PMC article.
Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations.
Neumann-Haefelin C, Oniangue-Ndza C, Kuntzen T, Schmidt J, Nitschke K, Sidney J, Caillet-Saguy C, Binder M, Kersting N, Kemper MW, Power KA, Ingber S, Reyor LL, Hills-Evans K, Kim AY, Lauer GM, Lohmann V, Sette A, Henn MR, Bressanelli S, Thimme R, Allen TM. Neumann-Haefelin C, et al. Among authors: sette a. Hepatology. 2011 Oct;54(4):1157-66. doi: 10.1002/hep.24541. Hepatology. 2011. PMID: 22006856 Free PMC article.
Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control.
Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, Sette A, Carrington M, Streeck H. Ranasinghe S, et al. Among authors: sette a. Nat Med. 2013 Jul;19(7):930-3. doi: 10.1038/nm.3229. Epub 2013 Jun 23. Nat Med. 2013. PMID: 23793098 Free PMC article.
HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope.
Nitschke K, Barriga A, Schmidt J, Timm J, Viazov S, Kuntzen T, Kim AY, Lauer GM, Allen TM, Gaudieri S, Rauch A, Lange CM, Sarrazin C, Eiermann T, Sidney J, Sette A, Thimme R, López D, Neumann-Haefelin C. Nitschke K, et al. Among authors: sette a. J Hepatol. 2014 Jan;60(1):22-9. doi: 10.1016/j.jhep.2013.08.009. Epub 2013 Aug 23. J Hepatol. 2014. PMID: 23978718 Free PMC article.
Human CD4+ T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity.
Angelo MA, Grifoni A, O'Rourke PH, Sidney J, Paul S, Peters B, de Silva AD, Phillips E, Mallal S, Diehl SA, Kirkpatrick BD, Whitehead SS, Durbin AP, Sette A, Weiskopf D. Angelo MA, et al. Among authors: sette a. J Virol. 2017 Feb 14;91(5):e02147-16. doi: 10.1128/JVI.02147-16. Print 2017 Mar 1. J Virol. 2017. PMID: 27974563 Free PMC article.
1,122 results