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Responder analysis to demonstrate the effect of targeting type 2 inflammatory mechanisms with dupilumab across objective and patient-reported endpoints for patients with severe chronic rhinosinusitis with nasal polyps in the SINUS-24 and SINUS-52 studies.
Bachert C, Peters AT, Heffler E, Han JK, Olze H, Pfaar O, Chuang CC, Rout R, Attre R, Goga L, Jacob-Nara JA, Rowe PJ, Deniz Y, Chen Z, Kamat S, Siddiqui S. Bachert C, et al. Among authors: siddiqui s. Clin Exp Allergy. 2022 Feb;52(2):244-249. doi: 10.1111/cea.14051. Clin Exp Allergy. 2022. PMID: 35092110 No abstract available.
Estimating Clinically Meaningful Change of Efficacy Outcomes in Inadequately Controlled Chronic Rhinosinusitis with Nasal Polyposis.
Han JK, Bachert C, Lee SE, Hopkins C, Heffler E, Hellings PW, Peters AT, Kamat S, Whalley D, Qin S, Nelson L, Siddiqui S, Khan AH, Li Y, Mannent LP, Guillemin I, Chuang CC. Han JK, et al. Among authors: siddiqui s. Laryngoscope. 2022 Feb;132(2):265-271. doi: 10.1002/lary.29888. Epub 2021 Dec 1. Laryngoscope. 2022. PMID: 34850966 Free PMC article.
Rapid and sustained effects of dupilumab in severe chronic rhinosinusitis with nasal polyps.
Hellings PW, Peters AT, Chaker AM, Heffler E, Zhang H, Praestgaard A, Nash S, Khan AH, Siddiqui S, Jacob-Nara JA, Rowe PJ, Deniz Y. Hellings PW, et al. Among authors: siddiqui s. Int Forum Allergy Rhinol. 2022 Jul;12(7):958-962. doi: 10.1002/alr.22944. Epub 2022 Jan 23. Int Forum Allergy Rhinol. 2022. PMID: 34911163 Free PMC article. No abstract available.
Dupilumab efficacy and biomarkers in chronic rhinosinusitis with nasal polyps: Association between dupilumab treatment effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS-24 and SINUS-52 trials.
Bachert C, Corren J, Lee SE, Zhang H, Harel S, Cunoosamy D, Khan AH, Jacob-Nara JA, Siddiqui S, Nash S, Rowe PJ, Deniz Y. Bachert C, et al. Among authors: siddiqui s. Int Forum Allergy Rhinol. 2022 Sep;12(9):1191-1195. doi: 10.1002/alr.22964. Epub 2022 Jan 31. Int Forum Allergy Rhinol. 2022. PMID: 34970860 Free PMC article. No abstract available.
Impact of dupilumab on SNOT-22 sleep and function scores in CRSwNP.
Busse WW, Wellman A, Diamant Z, Cohen NA, Chaker AM, Bachert C, Siddiqui S, Zhang H, Nash S, Khan AH, Jacob-Nara JA, Rowe PJ, Deniz Y. Busse WW, et al. Among authors: siddiqui s. J Allergy Clin Immunol Pract. 2022 Sep;10(9):2479-2482.e3. doi: 10.1016/j.jaip.2022.05.013. Epub 2022 May 24. J Allergy Clin Immunol Pract. 2022. PMID: 35618213 Free article. No abstract available.
Improvement in Health-Related Quality of Life with Dupilumab in Patients with Moderate-to-Severe Asthma with Comorbid Chronic Rhinosinusitis with/without Nasal Polyps: An Analysis of the QUEST Study.
Hopkins C, Buchheit KM, Heffler E, Cohen NA, Olze H, Khan AH, Msihid J, Siddiqui S, Nash S, Jacob-Nara JA, Rowe PJ, Deniz Y. Hopkins C, et al. Among authors: siddiqui s. J Asthma Allergy. 2022 Jun 7;15:767-773. doi: 10.2147/JAA.S363527. eCollection 2022. J Asthma Allergy. 2022. PMID: 35698581 Free PMC article.
Improvement in patient-reported "taste" and association with smell in dupilumab-treated patients with severe chronic rhinosinusitis with nasal polyps from the SINUS-24 and SINUS-52 trials.
Peters AT, Soler ZM, Kern RC, Heffler E, Maspero JF, Crampette L, Fujieda S, Lane AP, Zhang H, Nash S, Khan AH, Siddiqui S, Jacob-Nara JA, Rowe P, Deniz Y. Peters AT, et al. Among authors: siddiqui s. Clin Exp Allergy. 2022 Sep;52(9):1105-1109. doi: 10.1111/cea.14194. Epub 2022 Jul 12. Clin Exp Allergy. 2022. PMID: 35775319 Free PMC article. No abstract available.
Dupilumab efficacy and safety in Latin American patients with uncontrolled, moderate-to-severe asthma: phase 3 LIBERTY ASTHMA QUEST study.
Maspero JF, Cardona G, Schonffeldt P, Tolcachier A, González-Diaz SN, Yañez A, Galvao CE, Msihid J, Gall R, Siddiqui S, Rowe PJ, Deniz Y, Jacob-Nara JA, Djandji M. Maspero JF, et al. Among authors: siddiqui s. J Asthma. 2023 May;60(5):981-990. doi: 10.1080/02770903.2022.2115927. Epub 2022 Oct 17. J Asthma. 2023. PMID: 36066123 Clinical Trial.
2,271 results