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Molecular Engineering of Efficacious Mono-Valent Ultra-Long Acting Two-Chain Insulin-Fc Conjugates.
Tagmose TM, Pedersen KM, Pridal L, Stidsen CE, Pedersen MØ, Lin Z, Zhang Y, Wan Z, Ferreras M, Naver H, Nielsen PK, Cao Z, Wang Y, Lykke L, Christensen JL, Jensen VS, Manfè V, Pedersen TÅ, Johansson E, Madsen P, Kodra JT, Münzel M, De Maria L, Nishimura E, Kjeldsen TB. Tagmose TM, et al. Among authors: nishimura e. J Med Chem. 2022 Feb 10;65(3):2633-2645. doi: 10.1021/acs.jmedchem.1c02039. Epub 2022 Feb 1. J Med Chem. 2022. PMID: 35104142
Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor.
Kodra JT, Jørgensen AS, Andersen B, Behrens C, Brand CL, Christensen IT, Guldbrandt M, Jeppesen CB, Knudsen LB, Madsen P, Nishimura E, Sams C, Sidelmann UG, Pedersen RA, Lynn FC, Lau J. Kodra JT, et al. Among authors: nishimura e. J Med Chem. 2008 Sep 11;51(17):5387-96. doi: 10.1021/jm7015599. Epub 2008 Aug 16. J Med Chem. 2008. PMID: 18707090
Engineering of insulin receptor isoform-selective insulin analogues.
Glendorf T, Stidsen CE, Norrman M, Nishimura E, Sørensen AR, Kjeldsen T. Glendorf T, et al. Among authors: nishimura e. PLoS One. 2011;6(5):e20288. doi: 10.1371/journal.pone.0020288. Epub 2011 May 20. PLoS One. 2011. PMID: 21625452 Free PMC article.
287 results