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Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.
Dai XQ, Camunas-Soler J, Briant LJB, Dos Santos T, Spigelman AF, Walker EM, Arrojo E Drigo R, Bautista A, Jones RC, Avrahami D, Lyon J, Nie A, Smith N, Zhang Y, Johnson J, Manning Fox JE, Michelakis ED, Light PE, Kaestner KH, Kim SK, Rorsman P, Stein RW, Quake SR, MacDonald PE. Dai XQ, et al. Among authors: kim sk. Cell Metab. 2022 Feb 1;34(2):256-268.e5. doi: 10.1016/j.cmet.2021.12.021. Cell Metab. 2022. PMID: 35108513 Free PMC article.
Gene regulatory networks governing pancreas development.
Arda HE, Benitez CM, Kim SK. Arda HE, et al. Among authors: kim sk. Dev Cell. 2013 Apr 15;25(1):5-13. doi: 10.1016/j.devcel.2013.03.016. Dev Cell. 2013. PMID: 23597482 Free PMC article. Review.
Suppression of insulin production and secretion by a decretin hormone.
Alfa RW, Park S, Skelly KR, Poffenberger G, Jain N, Gu X, Kockel L, Wang J, Liu Y, Powers AC, Kim SK. Alfa RW, et al. Among authors: kim sk. Cell Metab. 2015 Feb 3;21(2):323-334. doi: 10.1016/j.cmet.2015.01.006. Cell Metab. 2015. PMID: 25651184 Free PMC article.
Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.
Arda HE, Li L, Tsai J, Torre EA, Rosli Y, Peiris H, Spitale RC, Dai C, Gu X, Qu K, Wang P, Wang J, Grompe M, Scharfmann R, Snyder MS, Bottino R, Powers AC, Chang HY, Kim SK. Arda HE, et al. Among authors: kim sk. Cell Metab. 2016 May 10;23(5):909-20. doi: 10.1016/j.cmet.2016.04.002. Epub 2016 Apr 28. Cell Metab. 2016. PMID: 27133132 Free PMC article.
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
Chakravarthy H, Gu X, Enge M, Dai X, Wang Y, Damond N, Downie C, Liu K, Wang J, Xing Y, Chera S, Thorel F, Quake S, Oberholzer J, MacDonald PE, Herrera PL, Kim SK. Chakravarthy H, et al. Among authors: kim sk. Cell Metab. 2017 Mar 7;25(3):622-634. doi: 10.1016/j.cmet.2017.01.009. Epub 2017 Feb 16. Cell Metab. 2017. PMID: 28215845 Free PMC article.
7,194 results