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363 results

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Page 1
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.
Yarmolinsky J, Díez-Obrero V, Richardson TG, Pigeyre M, Sjaarda J, Paré G, Walker VM, Vincent EE, Tan VY, Obón-Santacana M, Albanes D, Hampe J, Gsur A, Hampel H, Pai RK, Jenkins M, Gallinger S, Casey G, Zheng W, Amos CI; International Lung Cancer Consortium; PRACTICAL consortium; MEGASTROKE consortium; Smith GD, Martin RM, Moreno V. Yarmolinsky J, et al. Among authors: pai rk. PLoS Med. 2022 Feb 3;19(2):e1003897. doi: 10.1371/journal.pmed.1003897. eCollection 2022 Feb. PLoS Med. 2022. PMID: 35113855 Free PMC article.
Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer.
Matejcic M, Shaban HA, Quintana MW, Schumacher FR, Edlund CK, Naghi L, Pai RK, Haile RW, Levine AJ, Buchanan DD, Jenkins MA, Figueiredo JC, Rennert G, Gruber SB, Li L, Casey G, Conti DV, Schmit SL. Matejcic M, et al. Among authors: pai rk. Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):895-903. doi: 10.1158/1055-9965.EPI-20-1457. Epub 2021 Feb 24. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 33627384 Free PMC article.
Assessment of a Polygenic Risk Score for Colorectal Cancer to Predict Risk of Lynch Syndrome Colorectal Cancer.
Jenkins MA, Buchanan DD, Lai J, Makalic E, Dite GS, Win AK, Clendenning M, Winship IM, Hayes RB, Huyghe JR, Peters U, Gallinger S, Marchand LL, Figueiredo JC, Pai RK, Newcomb PA, Church JM, Casey G, Hopper JL. Jenkins MA, et al. Among authors: pai rk. JNCI Cancer Spectr. 2021 Mar 8;5(2):pkab022. doi: 10.1093/jncics/pkab022. eCollection 2021 Apr. JNCI Cancer Spectr. 2021. PMID: 33928216 Free PMC article.
Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study.
Hua X, Dai JY, Lindström S, Harrison TA, Lin Y, Alberts SR, Alwers E, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Casey G, Chang-Claude J, Gallinger S, Giles GG, Goldberg RM, Gunter MJ, Hoffmeister M, Jenkins MA, Joshi AD, Ma W, Milne RL, Murphy N, Pai RK, Sakoda LC, Schoen RE, Shi Q, Slattery ML, Song M, White E, Marchand LL, Chan AT, Peters U, Newcomb PA. Hua X, et al. Among authors: pai rk. Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1349-1358. doi: 10.1158/1055-9965.EPI-20-1848. Epub 2021 May 10. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 33972368 Free PMC article.
Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer.
Archambault AN, Lin Y, Jeon J, Harrison TA, Bishop DT, Brenner H, Casey G, Chan AT, Chang-Claude J, Figueiredo JC, Gallinger S, Gruber SB, Gunter MJ, Hoffmeister M, Jenkins MA, Keku TO, Marchand LL, Li L, Moreno V, Newcomb PA, Pai R, Parfrey PS, Rennert G, Sakoda LC, Sandler RS, Slattery ML, Song M, Win AK, Woods MO, Murphy N, Campbell PT, Su YR, Zeleniuch-Jacquotte A, Liang PS, Du M, Hsu L, Peters U, Hayes RB. Archambault AN, et al. JNCI Cancer Spectr. 2021 May 20;5(3):pkab029. doi: 10.1093/jncics/pkab029. eCollection 2021 Jun. JNCI Cancer Spectr. 2021. PMID: 34041438 Free PMC article.
Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex-specific and lifestyle factors specific associations.
Huang Y, Hua X, Labadie JD, Harrison TA, Dai JY, Lindstrom S, Lin Y, Berndt SI, Buchanan DD, Campbell PT, Casey G, Gallinger SJ, Gunter MJ, Hoffmeister M, Jenkins MA, Sakoda LC, Schoen RE, Diergaarde B, Slattery ML, White E, Giles G, Brenner H, Chang-Claude J, Joshi A, Ma W, Pai RK, Chan AT, Peters U, Newcomb PA. Huang Y, et al. Among authors: pai rk. Int J Cancer. 2022 May 1;150(9):1447-1454. doi: 10.1002/ijc.33897. Epub 2022 Jan 13. Int J Cancer. 2022. PMID: 34888857 Free PMC article.
Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival.
Labadie JD, Savas S, Harrison TA, Banbury B, Huang Y, Buchanan DD, Campbell PT, Gallinger SJ, Giles GG, Gunter MJ, Hoffmeister M, Hsu L, Jenkins MA, Lin Y, Ogino S, Phipps AI, Slattery ML, Steinfelder RS, Sun W, Van Guelpen B, Hua X, Figuieredo JC, Pai RK, Nassir R, Qi L, Chan AT, Peters U, Newcomb PA. Labadie JD, et al. Among authors: pai rk. Sci Rep. 2022 Jan 7;12(1):127. doi: 10.1038/s41598-021-03945-x. Sci Rep. 2022. PMID: 34996992 Free PMC article.
Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study.
Archambault AN, Jeon J, Lin Y, Thomas M, Harrison TA, Bishop DT, Brenner H, Casey G, Chan AT, Chang-Claude J, Figueiredo JC, Gallinger S, Gruber SB, Gunter MJ, Guo F, Hoffmeister M, Jenkins MA, Keku TO, Le Marchand L, Li L, Moreno V, Newcomb PA, Pai R, Parfrey PS, Rennert G, Sakoda LC, Lee JK, Slattery ML, Song M, Win AK, Woods MO, Murphy N, Campbell PT, Su YR, Lansdorp-Vogelaar I, Peterse EFP, Cao Y, Zeleniuch-Jacquotte A, Liang PS, Du M, Corley DA, Hsu L, Peters U, Hayes RB. Archambault AN, et al. J Natl Cancer Inst. 2022 Apr 11;114(4):528-539. doi: 10.1093/jnci/djac003. J Natl Cancer Inst. 2022. PMID: 35026030 Free PMC article.
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.
Murphy N, Song M, Papadimitriou N, Carreras-Torres R, Langenberg C, Martin RM, Tsilidis KK, Barroso I, Chen J, Frayling TM, Bull CJ, Vincent EE, Cotterchio M, Gruber SB, Pai RK, Newcomb PA, Perez-Cornago A, van Duijnhoven FJB, Van Guelpen B, Vodicka P, Wolk A, Wu AH, Peters U, Chan AT, Gunter MJ. Murphy N, et al. Among authors: pai rk. J Natl Cancer Inst. 2022 May 9;114(5):740-752. doi: 10.1093/jnci/djac011. J Natl Cancer Inst. 2022. PMID: 35048991 Free PMC article.
Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer.
Barfield R, Huyghe JR, Lemire M, Dong X, Su YR, Brezina S, Buchanan DD, Figueiredo JC, Gallinger S, Giannakis M, Gsur A, Gunter MJ, Hampel H, Harrison TA, Hopper JL, Hudson TJ, Li CI, Moreno V, Newcomb PA, Pai RK, Pharoah PDP, Phipps AI, Qu C, Steinfelder RS, Sun W, Win AK, Zaidi SH, Campbell PT, Peters U, Hsu L. Barfield R, et al. Among authors: pai rk. Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1068-1076. doi: 10.1158/1055-9965.EPI-21-0724. Cancer Epidemiol Biomarkers Prev. 2022. PMID: 35247911 Free PMC article.
363 results