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Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates.
Du Y, Liang Z, Wang S, Sun D, Wang X, Liew SY, Lu S, Wu S, Jiang Y, Wang Y, Zhang B, Yu W, Lu Z, Pu Y, Zhang Y, Long H, Xiao S, Liang R, Zhang Z, Guan J, Wang J, Ren H, Wei Y, Zhao J, Sun S, Liu T, Meng G, Wang L, Gu J, Wang T, Liu Y, Li C, Tang C, Shen Z, Peng X, Deng H. Du Y, et al. Among authors: peng x. Nat Med. 2022 Feb;28(2):272-282. doi: 10.1038/s41591-021-01645-7. Epub 2022 Feb 3. Nat Med. 2022. PMID: 35115708
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Yang J, Wang W, Chen Z, Lu S, Yang F, Bi Z, Bao L, Mo F, Li X, Huang Y, Hong W, Yang Y, Zhao Y, Ye F, Lin S, Deng W, Chen H, Lei H, Zhang Z, Luo M, Gao H, Zheng Y, Gong Y, Jiang X, Xu Y, Lv Q, Li D, Wang M, Li F, Wang S, Wang G, Yu P, Qu Y, Yang L, Deng H, Tong A, Li J, Wang Z, Yang J, Shen G, Zhao Z, Li Y, Luo J, Liu H, Yu W, Yang M, Xu J, Wang J, Li H, Wang H, Kuang D, Lin P, Hu Z, Guo W, Cheng W, He Y, Song X, Chen C, Xue Z, Yao S, Chen L, Ma X, Chen S, Gou M, Huang W, Wang Y, Fan C, Tian Z, Shi M, Wang FS, Dai L, Wu M, Li G, Wang G, Peng Y, Qian Z, Huang C, Lau JY, Yang Z, Wei Y, Cen X, Peng X, Qin C, Zhang K, Lu G, Wei X. Yang J, et al. Among authors: peng y, peng x. Nature. 2020 Oct;586(7830):572-577. doi: 10.1038/s41586-020-2599-8. Epub 2020 Jul 29. Nature. 2020. PMID: 32726802
Comparison of nonhuman primates identified the suitable model for COVID-19.
Lu S, Zhao Y, Yu W, Yang Y, Gao J, Wang J, Kuang D, Yang M, Yang J, Ma C, Xu J, Qian X, Li H, Zhao S, Li J, Wang H, Long H, Zhou J, Luo F, Ding K, Wu D, Zhang Y, Dong Y, Liu Y, Zheng Y, Lin X, Jiao L, Zheng H, Dai Q, Sun Q, Hu Y, Ke C, Liu H, Peng X. Lu S, et al. Among authors: peng x. Signal Transduct Target Ther. 2020 Oct 19;5(1):157. doi: 10.1038/s41392-020-00269-6. Signal Transduct Target Ther. 2020. PMID: 32814760 Free PMC article.
Susceptibility of tree shrew to SARS-CoV-2 infection.
Zhao Y, Wang J, Kuang D, Xu J, Yang M, Ma C, Zhao S, Li J, Long H, Ding K, Gao J, Liu J, Wang H, Li H, Yang Y, Yu W, Yang J, Zheng Y, Wu D, Lu S, Liu H, Peng X. Zhao Y, et al. Among authors: peng x. Sci Rep. 2020 Sep 29;10(1):16007. doi: 10.1038/s41598-020-72563-w. Sci Rep. 2020. PMID: 32994418 Free PMC article.
A mouse model for SARS-CoV-2-induced acute respiratory distress syndrome.
Hong W, Yang J, Bi Z, He C, Lei H, Yu W, Yang Y, Fan C, Lu S, Peng X, Wei X. Hong W, et al. Among authors: peng x. Signal Transduct Target Ther. 2021 Jan 1;6(1):1. doi: 10.1038/s41392-020-00451-w. Signal Transduct Target Ther. 2021. PMID: 33384407 Free PMC article. No abstract available.
The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys.
Jiao L, Yang Y, Yu W, Zhao Y, Long H, Gao J, Ding K, Ma C, Li J, Zhao S, Wang H, Li H, Yang M, Xu J, Wang J, Yang J, Kuang D, Luo F, Qian X, Xu L, Yin B, Liu W, Liu H, Lu S, Peng X. Jiao L, et al. Among authors: peng x. Signal Transduct Target Ther. 2021 Apr 24;6(1):169. doi: 10.1038/s41392-021-00591-7. Signal Transduct Target Ther. 2021. PMID: 33895780 Free PMC article.
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