Tong JJ - Search Results

1

Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation.

Minogue PJ, Tong JJ, Wichmann K, Mysliwiec H, Ebihara L, Beyer EC, Berthoud VM. Minogue PJ, et al. Among authors: tong jj. J Biol Chem. 2022 Mar;298(3):101673. doi: 10.1016/j.jbc.2022.101673. Epub 2022 Feb 2. J Biol Chem. 2022. PMID: 35120923 Free PMC article.

2

A mutant connexin50 with enhanced hemichannel function leads to cell death.

Minogue PJ, Tong JJ, Arora A, Russell-Eggitt I, Hunt DM, Moore AT, Ebihara L, Beyer EC, Berthoud VM. Minogue PJ, et al. Among authors: tong jj. Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5837-45. doi: 10.1167/iovs.09-3759. Epub 2009 Aug 13. Invest Ophthalmol Vis Sci. 2009. PMID: 19684000 Free PMC article.

3

Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50.

Tong JJ, Minogue PJ, Guo W, Chen TL, Beyer EC, Berthoud VM, Ebihara L. Tong JJ, et al. Am J Physiol Cell Physiol. 2011 May;300(5):C1055-64. doi: 10.1152/ajpcell.00384.2010. Epub 2011 Jan 12. Am J Physiol Cell Physiol. 2011. PMID: 21228318 Free PMC article.

4

The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating.

Tong JJ, Minogue PJ, Kobeszko M, Beyer EC, Berthoud VM, Ebihara L. Tong JJ, et al. J Membr Biol. 2015 Feb;248(1):145-55. doi: 10.1007/s00232-014-9752-y. Epub 2014 Nov 18. J Membr Biol. 2015. PMID: 25404239 Free PMC article.

5

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant.

Tong JJ, Khan U, Haddad BG, Minogue PJ, Beyer EC, Berthoud VM, Reichow SL, Ebihara L. Tong JJ, et al. Biophys J. 2021 Dec 21;120(24):5644-5656. doi: 10.1016/j.bpj.2021.11.004. Epub 2021 Nov 9. Biophys J. 2021. PMID: 34762867 Free PMC article.

6

Exchange of gating properties between rat cx46 and chicken cx45.6.

Tong JJ, Liu X, Dong L, Ebihara L. Tong JJ, et al. Biophys J. 2004 Oct;87(4):2397-406. doi: 10.1529/biophysj.104.039594. Biophys J. 2004. PMID: 15454438 Free PMC article.

7

Structural determinants for the differences in voltage gating of chicken Cx56 and Cx45.6 gap-junctional hemichannels.

Tong JJ, Ebihara L. Tong JJ, et al. Biophys J. 2006 Sep 15;91(6):2142-54. doi: 10.1529/biophysj.106.082859. Epub 2006 Jun 23. Biophys J. 2006. PMID: 16798801 Free PMC article.

8

The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation.

Graw J, Schmidt W, Minogue PJ, Rodriguez J, Tong JJ, Klopp N, Illig T, Ebihara L, Berthoud VM, Beyer EC. Graw J, et al. Among authors: tong jj. Mol Vis. 2009 Sep 14;15:1881-5. Mol Vis. 2009. PMID: 19756179 Free PMC article.

9

Properties of connexin 46 hemichannels in dissociated lens fiber cells.

Ebihara L, Tong JJ, Vertel B, White TW, Chen TL. Ebihara L, et al. Among authors: tong jj. Invest Ophthalmol Vis Sci. 2011 Feb 22;52(2):882-9. doi: 10.1167/iovs.10-6200. Print 2011 Feb. Invest Ophthalmol Vis Sci. 2011. PMID: 20861491 Free PMC article.

10

Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46.

Tong JJ, Sohn BC, Lam A, Walters DE, Vertel BM, Ebihara L. Tong JJ, et al. Am J Physiol Cell Physiol. 2013 May 1;304(9):C823-32. doi: 10.1152/ajpcell.00344.2012. Epub 2013 Jan 9. Am J Physiol Cell Physiol. 2013. PMID: 23302783 Free PMC article.

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