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Page 1
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Wolff DW, Deng Z, Bianchi-Smiraglia A, Foley CE, Han Z, Wang X, Shen S, Rosenberg MM, Moparthy S, Yun DH, Chen J, Baker BK, Roll MV, Magiera AJ, Li J, Hurley E, Feltri ML, Cox AO, Lee J, Furdui CM, Liu L, Bshara W, LaConte LEW, Kandel ES, Pasquale EB, Qu J, Hedstrom L, Nikiforov MA. Wolff DW, et al. Among authors: nikiforov ma. Cell Chem Biol. 2022 Jun 16;29(6):970-984.e6. doi: 10.1016/j.chembiol.2022.01.007. Epub 2022 Feb 10. Cell Chem Biol. 2022. PMID: 35148834 Free PMC article.
Controversial aspects of oncogene-induced senescence.
Bianchi-Smiraglia A, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: nikiforov ma. Cell Cycle. 2012 Nov 15;11(22):4147-51. doi: 10.4161/cc.22589. Epub 2012 Oct 24. Cell Cycle. 2012. PMID: 23095636 Free PMC article. Review.
Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion.
Mannava S, Moparthy KC, Wheeler LJ, Leonova KI, Wawrzyniak JA, Bianchi-Smiraglia A, Berman AE, Flanagan S, Shewach DS, Zeitouni NC, Gudkov AV, Mathews CK, Nikiforov MA. Mannava S, et al. Among authors: nikiforov ma. Aging (Albany NY). 2012 Dec;4(12):917-22. doi: 10.18632/aging.100512. Aging (Albany NY). 2012. PMID: 23249808 Free PMC article.
A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.
Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, Mannava S, Ackroyd J, Bagati A, Omilian AR, Im M, Fedtsova N, Miecznikowski JC, Moparthy KC, Zucker SN, Zhu Q, Kozlova NI, Berman AE, Hoek KS, Gudkov AV, Shewach DS, Morrison CD, Nikiforov MA. Wawrzyniak JA, et al. Among authors: nikiforov ma. Cell Rep. 2013 Oct 31;5(2):493-507. doi: 10.1016/j.celrep.2013.09.015. Epub 2013 Oct 17. Cell Rep. 2013. PMID: 24139804 Free PMC article.
Nrf2 amplifies oxidative stress via induction of Klf9.
Zucker SN, Fink EE, Bagati A, Mannava S, Bianchi-Smiraglia A, Bogner PN, Wawrzyniak JA, Foley C, Leonova KI, Grimm MJ, Moparthy K, Ionov Y, Wang J, Liu S, Sexton S, Kandel ES, Bakin AV, Zhang Y, Kaminski N, Segal BH, Nikiforov MA. Zucker SN, et al. Among authors: nikiforov ma. Mol Cell. 2014 Mar 20;53(6):916-928. doi: 10.1016/j.molcel.2014.01.033. Epub 2014 Mar 6. Mol Cell. 2014. PMID: 24613345 Free PMC article.
Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.
Bianchi-Smiraglia A, Wawrzyniak JA, Bagati A, Marvin EK, Ackroyd J, Moparthy S, Bshara W, Fink EE, Foley CE, Morozevich GE, Berman AE, Shewach DS, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: nikiforov ma. Cell Death Differ. 2015 Nov;22(11):1858-64. doi: 10.1038/cdd.2015.47. Epub 2015 Apr 24. Cell Death Differ. 2015. PMID: 25909885 Free PMC article.
Slowing down the Grand Touring Prototype speed of cancer cells.
Bianchi-Smiraglia A, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: nikiforov ma. Mol Cell Oncol. 2016 Jan 2;3(1):e1052181. doi: 10.1080/23723556.2015.1052181. Epub 2015 Jun 10. Mol Cell Oncol. 2016. PMID: 26989767 Free PMC article.
Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools.
Bianchi-Smiraglia A, Bagati A, Fink EE, Moparthy S, Wawrzyniak JA, Marvin EK, Battaglia S, Jowdy P, Kolesnikova M, Foley CE, Berman AE, Kozlova NI, Lipchick BC, Paul-Rosner LM, Bshara W, Ackroyd JJ, Shewach DS, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: nikiforov ma. Oncogene. 2017 Jan 5;36(1):84-96. doi: 10.1038/onc.2016.178. Epub 2016 May 16. Oncogene. 2017. PMID: 27181209 Free PMC article.
The Immortal Senescence.
Bianchi-Smiraglia A, Lipchick BC, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: nikiforov ma. Methods Mol Biol. 2017;1534:1-15. doi: 10.1007/978-1-4939-6670-7_1. Methods Mol Biol. 2017. PMID: 27812863 Free PMC article. Review.
Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution.
Bianchi-Smiraglia A, Rana MS, Foley CE, Paul LM, Lipchick BC, Moparthy S, Moparthy K, Fink EE, Bagati A, Hurley E, Affronti HC, Bakin AV, Kandel ES, Smiraglia DJ, Feltri ML, Sousa R, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: nikiforov ma. Nat Methods. 2017 Oct;14(10):1003-1009. doi: 10.1038/nmeth.4404. Epub 2017 Sep 4. Nat Methods. 2017. PMID: 28869758 Free PMC article.
67 results