Mols R - Search Results

1

The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern.

Abdelnabi R, Foo CS, Jochmans D, Vangeel L, De Jonghe S, Augustijns P, Mols R, Weynand B, Wattanakul T, Hoglund RM, Tarning J, Mowbray CE, Sjö P, Escudié F, Scandale I, Chatelain E, Neyts J. Abdelnabi R, et al. Among authors: mols r. Nat Commun. 2022 Feb 15;13(1):719. doi: 10.1038/s41467-022-28354-0. Nat Commun. 2022. PMID: 35169114 Free PMC article.

2

Apricot extract inhibits the P-gp-mediated efflux of talinolol.

Deferme S, Mols R, Van Driessche W, Augustijns P. Deferme S, et al. Among authors: mols r. J Pharm Sci. 2002 Dec;91(12):2539-48. doi: 10.1002/jps.10262. J Pharm Sci. 2002. PMID: 12434397

3

Metabolism of stevioside in pigs and intestinal absorption characteristics of stevioside, rebaudioside A and steviol.

Geuns JM, Augustijns P, Mols R, Buyse JG, Driessen B. Geuns JM, et al. Among authors: mols r. Food Chem Toxicol. 2003 Nov;41(11):1599-607. doi: 10.1016/s0278-6915(03)00191-1. Food Chem Toxicol. 2003. PMID: 12963013

4

HPLC with programmed wavelength fluorescence detection for the simultaneous determination of marker compounds of integrity and P-gp functionality in the Caco-2 intestinal absorption model.

Augustijns P, Mols R. Augustijns P, et al. Among authors: mols r. J Pharm Biomed Anal. 2004 Mar 10;34(5):971-8. doi: 10.1016/j.jpba.2003.11.016. J Pharm Biomed Anal. 2004. PMID: 15019031

5

Sulfasalazine transport in in-vitro, ex-vivo and in-vivo absorption models: contribution of efflux carriers and their modulation by co-administration of synthetic nature-identical fruit extracts.

Mols R, Deferme S, Augustijns P. Mols R, et al. J Pharm Pharmacol. 2005 Dec;57(12):1565-73. doi: 10.1211/jpp.57.12.0006. J Pharm Pharmacol. 2005. PMID: 16354400

6

Multidrug resistance-associated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites.

Mallants R, Van Oosterwyck K, Van Vaeck L, Mols R, De Clercq E, Augustijns P. Mallants R, et al. Among authors: mols r. Xenobiotica. 2005 Oct-Nov;35(10-11):1055-66. doi: 10.1080/00498250500354493. Xenobiotica. 2005. PMID: 16393861

7

Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.

Mellaerts R, Mols R, Jammaer JA, Aerts CA, Annaert P, Van Humbeeck J, Van den Mooter G, Augustijns P, Martens JA. Mellaerts R, et al. Among authors: mols r. Eur J Pharm Biopharm. 2008 May;69(1):223-30. doi: 10.1016/j.ejpb.2007.11.006. Epub 2007 Nov 23. Eur J Pharm Biopharm. 2008. PMID: 18164930

8

Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: evaluation of a novel tool in biopharmaceutical drug profiling.

Mols R, Brouwers J, Schinkel AH, Annaert P, Augustijns P. Mols R, et al. Drug Metab Dispos. 2009 Jun;37(6):1334-7. doi: 10.1124/dmd.109.026591. Epub 2009 Mar 9. Drug Metab Dispos. 2009. PMID: 19273528

9

In situ intestinal perfusion in knockout mice demonstrates inhibition of intestinal p-glycoprotein by ritonavir causing increased darunavir absorption.

Holmstock N, Mols R, Annaert P, Augustijns P. Holmstock N, et al. Among authors: mols r. Drug Metab Dispos. 2010 Sep;38(9):1407-10. doi: 10.1124/dmd.110.032771. Epub 2010 Jun 15. Drug Metab Dispos. 2010. PMID: 20551242

10

Validation of a differential in situ perfusion method with mesenteric blood sampling in rats for intestinal drug interaction profiling.

Brouwers J, Mols R, Annaert P, Augustijns P. Brouwers J, et al. Among authors: mols r. Biopharm Drug Dispos. 2010 Jul;31(5-6):278-85. doi: 10.1002/bdd.710. Biopharm Drug Dispos. 2010. PMID: 20578213

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