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The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern.
Abdelnabi R, Foo CS, Jochmans D, Vangeel L, De Jonghe S, Augustijns P, Mols R, Weynand B, Wattanakul T, Hoglund RM, Tarning J, Mowbray CE, Sjö P, Escudié F, Scandale I, Chatelain E, Neyts J. Abdelnabi R, et al. Among authors: scandale i. Nat Commun. 2022 Feb 15;13(1):719. doi: 10.1038/s41467-022-28354-0. Nat Commun. 2022. PMID: 35169114 Free PMC article.
Antitrypanosomal activity of fexinidazole metabolites, potential new drug candidates for Chagas disease.
Bahia MT, Nascimento AF, Mazzeti AL, Marques LF, Gonçalves KR, Mota LW, Diniz Lde F, Caldas IS, Talvani A, Shackleford DM, Koltun M, Saunders J, White KL, Scandale I, Charman SA, Chatelain E. Bahia MT, et al. Among authors: scandale i. Antimicrob Agents Chemother. 2014 Aug;58(8):4362-70. doi: 10.1128/AAC.02754-13. Epub 2014 May 19. Antimicrob Agents Chemother. 2014. PMID: 24841257 Free PMC article.
Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2.
Driouich JS, Cochin M, Touret F, Petit PR, Gilles M, Moureau G, Barthélémy K, Laprie C, Wattanakul T, Chotsiri P, Hoglund RM, Tarning J, Fraisse L, Sjö P, Mowbray CE, Escudié F, Scandale I, Chatelain E, de Lamballerie X, Solas C, Nougairède A. Driouich JS, et al. Among authors: scandale i. EBioMedicine. 2022 Aug;82:104148. doi: 10.1016/j.ebiom.2022.104148. Epub 2022 Jul 11. EBioMedicine. 2022. PMID: 35834886 Free PMC article.
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.
Assmus F, Driouich JS, Abdelnabi R, Vangeel L, Touret F, Adehin A, Chotsiri P, Cochin M, Foo CS, Jochmans D, Kim S, Luciani L, Moureau G, Park S, Pétit PR, Shum D, Wattanakul T, Weynand B, Fraisse L, Ioset JR, Mowbray CE, Owen A, Hoglund RM, Tarning J, Lamballerie X, Nougairède A, Neyts J, Sjö P, Escudié F, Scandale I, Chatelain E. Assmus F, et al. Among authors: scandale i. Microorganisms. 2022 Aug 12;10(8):1639. doi: 10.3390/microorganisms10081639. Microorganisms. 2022. PMID: 36014057 Free PMC article.
Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure.
Francisco AF, Saade U, Jayawardhana S, Pottel H, Scandale I, Chatelain E, Liehl P, Kelly JM, Zrein M. Francisco AF, et al. Among authors: scandale i. PLoS Negl Trop Dis. 2022 Oct 3;16(10):e0010827. doi: 10.1371/journal.pntd.0010827. eCollection 2022 Oct. PLoS Negl Trop Dis. 2022. PMID: 36190992 Free PMC article.
State-of-the-Art in the Drug Discovery Pathway for Chagas Disease: A Framework for Drug Development and Target Validation.
Gabaldón-Figueira JC, Martinez-Peinado N, Escabia E, Ros-Lucas A, Chatelain E, Scandale I, Gascon J, Pinazo MJ, Alonso-Padilla J. Gabaldón-Figueira JC, et al. Among authors: scandale i. Res Rep Trop Med. 2023 Jun 14;14:1-19. doi: 10.2147/RRTM.S415273. eCollection 2023. Res Rep Trop Med. 2023. PMID: 37337597 Free PMC article. Review.
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
Box HJ, Sharp J, Pennington SH, Kijak E, Tatham L, Caygill CH, Lopeman RC, Jeffreys LN, Herriott J, Neary M, Valentijn A, Pertinez H, Curley P, Arshad U, Rajoli RKR, Jochmans D, Vangeel L, Neyts J, Chatelain E, Escudié F, Scandale I, Rannard S, Stewart JP, Biagini GA, Owen A. Box HJ, et al. Among authors: scandale i. J Antimicrob Chemother. 2024 Jan 3;79(1):172-178. doi: 10.1093/jac/dkad362. J Antimicrob Chemother. 2024. PMID: 37995258 Free PMC article.
36 results