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Page 1
Predicting nonlinear relationships between external and internal concentrations with physiologically based pharmacokinetic modeling.
Hoer D, Barton HA, Paini A, Bartels M, Ingle B, Domoradzki J, Fisher J, Embry M, Villanueva P, Miller D, Nguyen J, Zhang Q, Edwards SW, Tan YM. Hoer D, et al. Among authors: embry m. Toxicol Appl Pharmacol. 2022 Apr 1;440:115922. doi: 10.1016/j.taap.2022.115922. Epub 2022 Feb 15. Toxicol Appl Pharmacol. 2022. PMID: 35176293 Free PMC article.
Assessment of metabolic stability using the rainbow trout (Oncorhynchus mykiss) liver S9 fraction.
Johanning K, Hancock G, Escher B, Adekola A, Bernhard MJ, Cowan-Ellsberry C, Domoradzki J, Dyer S, Eickhoff C, Embry M, Erhardt S, Fitzsimmons P, Halder M, Hill J, Holden D, Johnson R, Rutishauser S, Segner H, Schultz I, Nichols J. Johanning K, et al. Among authors: embry m. Curr Protoc Toxicol. 2012 Aug;Chapter 14:Unit 14.10.1-28. doi: 10.1002/0471140856.tx1410s53. Curr Protoc Toxicol. 2012. PMID: 22896006
Adverse outcome pathways: From research to regulation scientific workshop report.
Kleinstreuer NC, Sullivan K, Allen D, Edwards S, Mendrick DL, Embry M, Matheson J, Rowlands JC, Munn S, Maull E, Casey W. Kleinstreuer NC, et al. Among authors: embry m. Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14. Regul Toxicol Pharmacol. 2016. PMID: 26774756 Free PMC article.
PBPK model reporting template for chemical risk assessment applications.
Tan YM, Chan M, Chukwudebe A, Domoradzki J, Fisher J, Hack CE, Hinderliter P, Hirasawa K, Leonard J, Lumen A, Paini A, Qian H, Ruiz P, Wambaugh J, Zhang F, Embry M. Tan YM, et al. Among authors: embry m. Regul Toxicol Pharmacol. 2020 Aug;115:104691. doi: 10.1016/j.yrtph.2020.104691. Epub 2020 Jun 2. Regul Toxicol Pharmacol. 2020. PMID: 32502513 Free PMC article. Review.
Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment.
Tan YM, Barton HA, Boobis A, Brunner R, Clewell H, Cope R, Dawson J, Domoradzki J, Egeghy P, Gulati P, Ingle B, Kleinstreuer N, Lowe K, Lowit A, Mendez E, Miller D, Minucci J, Nguyen J, Paini A, Perron M, Phillips K, Qian H, Ramanarayanan T, Sewell F, Villanueva P, Wambaugh J, Embry M. Tan YM, et al. Among authors: embry m. Regul Toxicol Pharmacol. 2021 Dec;127:105070. doi: 10.1016/j.yrtph.2021.105070. Epub 2021 Oct 28. Regul Toxicol Pharmacol. 2021. PMID: 34718074 Free PMC article.
Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies.
Lowe K, Dawson J, Phillips K, Minucci J, Wambaugh JF, Qian H, Ramanarayanan T, Egeghy P, Ingle B, Brunner R, Mendez E, Embry M, Tan YM. Lowe K, et al. Among authors: embry m. Regul Toxicol Pharmacol. 2021 Dec;127:105073. doi: 10.1016/j.yrtph.2021.105073. Epub 2021 Oct 29. Regul Toxicol Pharmacol. 2021. PMID: 34743952 Free PMC article.
Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration.
Bishop PL, Brescia S, Brunner R, Casey W, Conlee-Griffin K, Currie RA, Domoradzki J, Embry M, Harris MI, Hartung T, Hilton GM, Hooberman B, Ingle B, Jang KJ, Kinter L, Krall C, Leedale J, Lowit A, Mehta J, Mendez E, Mingoia B, Munarriz E, Murphy L, Myer A, Ottoni A, Panzarea M, Perron M, Pina J, Ramsingh D, Sewell F, Swanson J, Tan YM, Terron A, Trainer MA, Valadares MC, Webb S, Webb E, Willett C, Wolf DC. Bishop PL, et al. Among authors: embry m. ALTEX. 2023;40(3):534-540. doi: 10.14573/altex.2302151. Epub 2023 Mar 8. ALTEX. 2023. PMID: 36888967 Free PMC article.
Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians--screening for estrogen, androgen and thyroid hormone disruption.
Scholz S, Renner P, Belanger SE, Busquet F, Davi R, Demeneix BA, Denny JS, Léonard M, McMaster ME, Villeneuve DL, Embry MR. Scholz S, et al. Among authors: embry mr. Crit Rev Toxicol. 2013 Jan;43(1):45-72. doi: 10.3109/10408444.2012.737762. Epub 2012 Nov 28. Crit Rev Toxicol. 2013. PMID: 23190036 Review.
Investigating alternatives to the fish early-life stage test: a strategy for discovering and annotating adverse outcome pathways for early fish development.
Villeneuve D, Volz DC, Embry MR, Ankley GT, Belanger SE, Léonard M, Schirmer K, Tanguay R, Truong L, Wehmas L. Villeneuve D, et al. Among authors: embry mr. Environ Toxicol Chem. 2014 Jan;33(1):158-69. doi: 10.1002/etc.2403. Epub 2013 Nov 19. Environ Toxicol Chem. 2014. PMID: 24115264 Free PMC article.
88 results