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Predicting nonlinear relationships between external and internal concentrations with physiologically based pharmacokinetic modeling.
Hoer D, Barton HA, Paini A, Bartels M, Ingle B, Domoradzki J, Fisher J, Embry M, Villanueva P, Miller D, Nguyen J, Zhang Q, Edwards SW, Tan YM. Hoer D, et al. Among authors: fisher j. Toxicol Appl Pharmacol. 2022 Apr 1;440:115922. doi: 10.1016/j.taap.2022.115922. Epub 2022 Feb 15. Toxicol Appl Pharmacol. 2022. PMID: 35176293 Free PMC article.
PBPK model reporting template for chemical risk assessment applications.
Tan YM, Chan M, Chukwudebe A, Domoradzki J, Fisher J, Hack CE, Hinderliter P, Hirasawa K, Leonard J, Lumen A, Paini A, Qian H, Ruiz P, Wambaugh J, Zhang F, Embry M. Tan YM, et al. Among authors: fisher j. Regul Toxicol Pharmacol. 2020 Aug;115:104691. doi: 10.1016/j.yrtph.2020.104691. Epub 2020 Jun 2. Regul Toxicol Pharmacol. 2020. PMID: 32502513 Free PMC article. Review.
Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates.
Yang X, Naylor J, Matazel K, Goodwin A, Jacob CC, Bryant M, Loukotková L, Gamboa da Costa G, Chemerynski S, Deng-Bryant Y, Reissig C, Jackson K, Fisher J. Yang X, et al. Among authors: fisher j. Toxicol Appl Pharmacol. 2020 Jan 1;386:114826. doi: 10.1016/j.taap.2019.114826. Epub 2019 Nov 12. Toxicol Appl Pharmacol. 2020. PMID: 31730783
6,256 results