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Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria.
Barker WT, Nemeth AM, Brackett SM, Basak AK, Chandler CE, Jania LA, Zuercher WJ, Melander RJ, Koller BH, Ernst RK, Melander C. Barker WT, et al. Among authors: chandler ce. ACS Infect Dis. 2019 Oct 11;5(10):1764-1771. doi: 10.1021/acsinfecdis.9b00212. Epub 2019 Sep 4. ACS Infect Dis. 2019. PMID: 31434474 Free PMC article.
Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria.
Barker WT, Martin SE, Chandler CE, Nguyen TV, Harris TL, Goodell C, Melander RJ, Doi Y, Ernst RK, Melander C. Barker WT, et al. Among authors: chandler ce. Bioorg Med Chem. 2017 Oct 15;25(20):5749-5753. doi: 10.1016/j.bmc.2017.08.055. Epub 2017 Sep 9. Bioorg Med Chem. 2017. PMID: 28958847 Free PMC article.
55 results