Wu JC - Search Results

1

Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy.

Chen SN, Lam CK, Wan YW, Gao S, Malak OA, Zhao SR, Lombardi R, Ambardekar AV, Bristow MR, Cleveland J, Gigli M, Sinagra G, Graw S, Taylor MRG, Wu JC, Mestroni L. Chen SN, et al. Among authors: wu jc. Sci Adv. 2022 Feb 25;8(8):eabk0052. doi: 10.1126/sciadv.abk0052. Epub 2022 Feb 23. Sci Adv. 2022. PMID: 35196083 Free PMC article.

2

Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells.

Ma N, Zhang JZ, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Ma N, et al. Among authors: wu h, wu jc. Circulation. 2018 Dec 4;138(23):2666-2681. doi: 10.1161/CIRCULATIONAHA.117.032273. Circulation. 2018. PMID: 29914921 Free PMC article.

3

Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant.

Garg P, Oikonomopoulos A, Chen H, Li Y, Lam CK, Sallam K, Perez M, Lux RL, Sanguinetti MC, Wu JC. Garg P, et al. Among authors: wu jc. J Am Coll Cardiol. 2018 Jul 3;72(1):62-75. doi: 10.1016/j.jacc.2018.04.041. J Am Coll Cardiol. 2018. PMID: 29957233 Free PMC article.

4

Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come?

Lam CK, Wu JC. Lam CK, et al. Among authors: wu jc. Eur Heart J. 2018 Nov 14;39(43):3893-3895. doi: 10.1093/eurheartj/ehy388. Eur Heart J. 2018. PMID: 30010924 Free PMC article. No abstract available.

5

A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.

Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, Ashley EA, Yang F, Karakikes I, Wu JC. Seeger T, et al. Among authors: wu jc. Circulation. 2019 Feb 5;139(6):799-811. doi: 10.1161/CIRCULATIONAHA.118.034624. Circulation. 2019. PMID: 30586709 Free PMC article.

6

Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer.

Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Kitani T, et al. Among authors: wu jc. Circulation. 2019 May 21;139(21):2451-2465. doi: 10.1161/CIRCULATIONAHA.118.037357. Circulation. 2019. PMID: 30866650 Free PMC article.

7

Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Lam CK, Tian L, Belbachir N, Wnorowski A, Shrestha R, Ma N, Kitani T, Rhee JW, Wu JC. Lam CK, et al. Among authors: wu jc. Circ Res. 2019 Jul 5;125(2):212-222. doi: 10.1161/CIRCRESAHA.118.314202. Epub 2019 May 13. Circ Res. 2019. PMID: 31079550 Free PMC article.

8

Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.

Wu H, Yang H, Rhee JW, Zhang JZ, Lam CK, Sallam K, Chang ACY, Ma N, Lee J, Zhang H, Blau HM, Bers DM, Wu JC. Wu H, et al. Among authors: wu jc. Eur Heart J. 2019 Dec 1;40(45):3685-3695. doi: 10.1093/eurheartj/ehz326. Eur Heart J. 2019. PMID: 31219556 Free PMC article.

9

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.

Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, Rhee JW, Churko JM, Chaudhary R, Chour T, Wang PJ, Snyder MP, Chang HY, Karakikes I, Wu JC. Lee J, et al. Among authors: wu h, wu jc. Nature. 2019 Aug;572(7769):335-340. doi: 10.1038/s41586-019-1406-x. Epub 2019 Jul 17. Nature. 2019. PMID: 31316208 Free PMC article.

10

Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Rhee JW, Yi H, Thomas D, Lam CK, Belbachir N, Tian L, Qin X, Malisa J, Lau E, Paik DT, Kim Y, Choi BS, Sayed N, Sallam K, Liao R, Wu JC. Rhee JW, et al. Among authors: wu jc. Cell Rep. 2020 Jul 14;32(2):107886. doi: 10.1016/j.celrep.2020.107886. Cell Rep. 2020. PMID: 32668256 Free PMC article.

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