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Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors.
Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, Chen Y, Dai A, Liang A, Ming Q, Wang M, Chen LN, Xu P, Chang R, Feng W, Xia T, Zhang Y, Wu B, Yang D, Zhao L, Xu HE, Wang MW. Zhao F, et al. Among authors: cong z. Nat Commun. 2022 Feb 25;13(1):1057. doi: 10.1038/s41467-022-28683-0. Nat Commun. 2022. PMID: 35217653 Free PMC article.
Structural basis for activation of the growth hormone-releasing hormone receptor.
Zhou F, Zhang H, Cong Z, Zhao LH, Zhou Q, Mao C, Cheng X, Shen DD, Cai X, Ma C, Wang Y, Dai A, Zhou Y, Sun W, Zhao F, Zhao S, Jiang H, Jiang Y, Yang D, Eric Xu H, Zhang Y, Wang MW. Zhou F, et al. Among authors: cong z. Nat Commun. 2020 Oct 15;11(1):5205. doi: 10.1038/s41467-020-18945-0. Nat Commun. 2020. PMID: 33060564 Free PMC article.
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Sun W, Chen LN, Zhou Q, Zhao LH, Yang D, Zhang H, Cong Z, Shen DD, Zhao F, Zhou F, Cai X, Chen Y, Zhou Y, Gadgaard S, van der Velden WJC, Zhao S, Jiang Y, Rosenkilde MM, Xu HE, Zhang Y, Wang MW. Sun W, et al. Among authors: cong z. Cell Res. 2020 Dec;30(12):1098-1108. doi: 10.1038/s41422-020-00442-0. Epub 2020 Nov 25. Cell Res. 2020. PMID: 33239759 Free PMC article.
GPR160 is a potential biomarker associated with prostate cancer.
Guo W, Zhang J, Zhou Y, Zhou C, Yang Y, Cong Z, Dong J, Yang D, Dai B, Wang MW. Guo W, et al. Among authors: cong z. Signal Transduct Target Ther. 2021 Jun 25;6(1):241. doi: 10.1038/s41392-021-00583-7. Signal Transduct Target Ther. 2021. PMID: 34168114 Free PMC article. No abstract available.
Constitutive signal bias mediated by the human GHRHR splice variant 1.
Cong Z, Zhou F, Zhang C, Zou X, Zhang H, Wang Y, Zhou Q, Cai X, Liu Q, Li J, Shao L, Mao C, Wang X, Wu J, Xia T, Zhao LH, Jiang H, Zhang Y, Xu HE, Cheng X, Yang D, Wang MW. Cong Z, et al. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2106606118. doi: 10.1073/pnas.2106606118. Proc Natl Acad Sci U S A. 2021. PMID: 34599099 Free PMC article.
Structural perspective of class B1 GPCR signaling.
Cong Z, Liang YL, Zhou Q, Darbalaei S, Zhao F, Feng W, Zhao L, Xu HE, Yang D, Wang MW. Cong Z, et al. Trends Pharmacol Sci. 2022 Apr;43(4):321-334. doi: 10.1016/j.tips.2022.01.002. Epub 2022 Jan 22. Trends Pharmacol Sci. 2022. PMID: 35078643 Free article. Review.
672 results